161 - Optimizing Reaction Conditions Through Design of Experiments (DoE) (S11E11)

This episode focuses on how the Design of Experiments (DoE) methodology is applied in organic process research and development to efficiently optimize reaction parameters. The advantages of Design of Experiments are highlighted by discussing the efficiency and cost saving properties in production. How to create the test, what sort of design is needed, and how to measure is laid out before.

What parameters are needed and the goal for each of those parameters is discussed to bring to light the ways to work it out. And the different options that can be used for analysis are discussed as well as what they all do and why they are of use. In closing, many reasons for testing in advance are highlighted.