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欢迎收听科研喵播客，用AI读文献，祝你效率百倍。访问labcat.com.cn下载。最新研究发现，多发性硬化症的病理生理学远不止于脑和脊髓中的典型病灶。研究者在《Acta neuropathologica》杂志上发表文章，探讨了正常外观的白质和灰质在疾病进展中的关键作用。这些看似正常的脑区实际上存在广泛的生化、细胞和微结构变化，可能是修复机制耗尽后，疾病恶化的驱动因素。这一发现不仅为理解多发性硬化症的疾病进展提供了更全面的视角，也为开发新的治疗策略，减缓或阻止残疾累积提供了新思路。
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