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科研喵使用AI读文献，祝你效率百倍，访问labcat.com.cn下载。最新研究发现，免疫受体SLAMF5在调节多发性硬化症（MS）中的髓系细胞介导的神经炎症中发挥关键作用。研究团队利用实验性自身免疫性脑脊髓炎（EAE）小鼠模型，发现SLAMF5缺乏可减少髓系细胞激活和共刺激分子表达，延缓疾病进展。此外，药物阻断SLAMF5可减缓病情发展，减少髓系细胞激活标志物表达。这项研究为治疗MS等自身免疫性疾病提供了新的治疗靶点，具有重要的临床意义。
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