383. What Really Causes Heart Disease? It’s Not Cholesterol - Dr. Malcolm Kendrick

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Malcolm and I explore the true causes of heart disease, challenging the conventional belief that cholesterol and LDL are the primary drivers. We dive into endothelial damage and blood clotting as the underlying mechanisms behind cardiovascular events, and unpack metabolic syndrome, statins, and the role of inflammation, toxins, and lifestyle factors in damaging blood vessels. Listen to the full interview to learn more.

Dr. Malcolm Kendrick is a Scottish physician, author, and researcher known for challenging mainstream views on cardiovascular disease. He is the author of The Clot Thickens, where he presents an alternative hypothesis that heart disease is driven by blood clotting and arterial damage rather than cholesterol. With decades of clinical experience, Kendrick has become a leading voice questioning traditional lipid-focused models of heart health.

We discuss the following:

• Saturated fat paradox
• Minnesota experiment explained
• Risk factors vs cholesterol
• Cholesterol narrative driven by profit
• Focus on disease process
• Glycocalyx and protection
• Small dense LDL debate
• Clot clearance and heart attack risk
• Stress impairs clot clearance
• Sunlight and nitric oxide
• Statins barely extend lifespan
• Lean mass hyper-responders explained

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EPISODE RESOURCES

• Dr. Malcolm Kendrick’s Website
• The Clot Thickens Book
• The Great Cholesterol Con Book
• Cardiovascular Blood Test

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*DISCLAIMER: This content is for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease. It should not replace professional medical advice.

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