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弗朗西斯·克里克与沃森合作破译DNA双螺旋模型，1953年联合在《自然》杂志上发表《核酸的分子结构——DNA的一种可能结构》的文章，便宣告了分子生物学时代的开启，被誉为是“生物学的一个标志，开创了新的时代”。
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