Approaching the AI Event Horizon? Part 2, w/ Abhi Mahajan, Helen Toner, Jeremie Harris, @8teAPi

Abhi Mahajan (@owlposting) explains how AI is reshaping biology and medicine, including foundation models to predict cancer treatment response and why he’s both skeptical and optimistic about current results. Helen Toner unpacks CSET’s “When AI Builds AI” report and why automated AI R&D is a major source of strategic surprise. Jeremie Harris then explores our lack of control over superhuman AI systems, fragile US–China coordination, and how to maintain situational awareness in a rapidly shifting landscape. Nathan uses Granola to uncover blind spots in conversations and AI research. Try it at granola.ai/tcr with code TCR — and if you’re already using it, test his blind spot recipe here: https://bit.ly/granolablindspot LINKS: Abhi Mahajan's Owl Posting site Heuristics for lab robotics article Deep Research on Noetik AI Sponsors: GovAI: GovAI was founded ten years ago on the belief that AI would end up transforming our world. Ten years later, the organization is at the forefront of trying to help decision-makers in government and industry navigate the transition to advanced AI.  GovAI is now hiring Research Scholars (one-year positions for those transitioning into AI policy) and Research Fellows (longer-term roles for experienced researchers). Both roles offer significant freedom to pursue policy research, advise decision-makers, or launch new initiatives. Applications close 22 February 2026. Apply at: https://www.governance.ai/opportunities Blitzy: Blitzy is the autonomous code generation platform that ingests millions of lines of code to accelerate enterprise software development by up to 5x with premium, spec-driven output. Schedule a strategy session with their AI solutions consultants at https://blitzy.com Tasklet: Tasklet is an AI agent that automates your work 24/7; just describe what you want in plain English and it gets the job done. Try it for free and use code COGREV for 50% off your first month at https://tasklet.ai Serval: Serval uses AI-powered automations to cut IT help desk tickets by more than 50%, freeing your team from repetitive tasks like password resets and onboarding. Book your free pilot and guarantee 50% help desk automation by week four at https://serval.com/cognitive Claude Claude is the AI collaborator that understands your entire workflow, from drafting and research to coding and complex problem-solving. Start tackling bigger problems with Claude and unlock Claude Pro’s full capabilities at ⁠⁠https://claude.ai/tcr⁠ PRODUCED BY: https://aipodcast.ing