Eliminating the SIDE EFFECTS of Medication

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Now, this information is very, very important

if you are on medications.

If you know of someone on medications,

send them this video,

because I'm gonna show you how to greatly reduce

the side effects from medication.

Now, one primary reason why a lot of people

have side effects from medication

has to do with something in your liver.

It's a certain group of enzymes

that help break down certain medications

and toxins as well.

And if that enzyme system is not working,

not only are you gonna experience more side effects,

but the medication could also not be as effective as it should.

Now, of course you already know this,

but I'm all about giving people alternatives to medication,

but there's certain people that need to be on medication.

And it's a really good thing to minimize the side effects.

And then at the end of this,

I'm gonna give you a download

that you can give your medical doctor

to help them look at a potential DNA problem

that you might have that can greatly alter

the type of medications that you're given.

And so I will talk about that at the end.

But let's first just talk about what is an enzyme?

An enzyme is a protein that speeds up

the chemical reaction in your body

millions of times faster

than if that enzyme wasn't working.

The great majority of medications work

by inhibiting certain enzymes.

For example, like an ACE inhibitor,

which inhibits this ACE enzyme

that affects the blood pressure,

like aspirin inhibits something called cox enzymes

that relate to inflammation.

And so enzymes speed up the reaction,

but what's really interesting about enzymes

is they don't seem to use their own energy

in this work that they do.

In other words, they can keep being recycled

and they seem to be very magical in that way.

The other thing about enzymes in order to make them work

is they need helper molecules.

They need, it's called cofactors or co-enzymes.

And those are basically vitamins and minerals.

And so now you know very simply

why we need vitamins and minerals

to allow these enzymes to work in our body.

And we have millions and millions

and millions of different enzymes in the body

that create all sorts of different effects.

But the primary enzymes I'm gonna talk about today

are called the phase one, phase two enzymes.

Now these are families of enzymes.

They're groups of enzymes.

They're not just one enzyme.

And the phase one enzymes in your liver

are called cytochrome P450 enzymes.

Again, there's a family of them.

And if there's any problem with this enzyme,

you're not gonna get the breakdown

or at least the start the breakdown of this drug

or toxin or whatever's trying to be broken down.

And then when you get into phase two,

which works with phase one, you have other enzyme groups

called glutathione enzymes.

So you have both of these working together

to take a poison, I'm sorry, medication and dismantle it

and then turn it into a harmless water soluble particle

that can be eliminated through the urine

or the sweat or the bowel.

And this doesn't just have to do with medication breakdown.

This has a lot to do with pesticides, herbicides,

fungicides, benzene from petroleum products

that you're exposed to, procarcinogens,

which are cancer causing things,

smoke, the chemicals in smoke, alcohol, estrogen.

So this enzyme system is very, very important.

Not necessarily just to reduce the side effects,

but also the effectiveness of a drug,

but also to prevent cancer because

a lot of these medications or toxins that you're exposed to,

if they're not fully broken down,

they can build up in the body and accumulate and create toxicity

and increase your risk for cancer and other problems.

Why am I talking about this right now?

Well, recently I'm doing a deep dive into genetics

and it's a fascinating topic

and there are certain problems that go on

with your DNA and your genes

that can end up causing a problem with your ability

to detoxify one section that I'm studying right now

is all about the detoxification genes.

And a big one, which is a common problem

is a mutation of this cytochrome P450 enzyme system.

There's over 2,000 different mutations

that you can have with this one gene

and it can lead to a lot of problems.

So if you get your DNA tested

and you find this being a problem,

then you need to work harder

on these detoxification enzymes

and it could be the reason why you are experiencing

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This is Andrew Huberman, host of the Huberman Lab podcast.

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Sorry, side effects from your medication in general.

So number one, you can have DNA mutations

with these enzymes.

Okay, that's number one.

Number two, you can have liver problems.

Let's see your liver is fatty or let's say it's inflamed

or let's say you have scar tissue as in cirrhosis.

This can decrease the function of these,

this phase one, phase two detoxification.

Also, if you're consuming grapefruit,

which is an inhibitor of this Enzyme,

the Cetacrome P450, that can be a problem

because what happens now, that medication that you take

starts to accumulate and it can create

a much bigger effect than it should.

And then also, certain medications can inhibit

that Enzyme too, like Warfarin and it depressants

and even statins.

So, your doctor needs to be aware of this.

A lot of this detoxification can then lead to inflammation.

And this is why even like the omega-3 fatty acids,

like from the fish oils or the cauliflower oil,

let our anti-inflammatory that support the heart.

And even some of the omega-6 fatty acids

that create inflammation also work with this enzyme.

So, again, if there's a problem with this enzyme

or your liver, you might not get the full benefit

of these fish oils or cauliflower oil when you're taking them.

You still feel inflamed.

So, the question is, how do we speed up

this phase one, phase two detoxification system?

Well, you're in luck because certain vegetables help

to trigger this enzyme system.

So, in other words, it causes these enzymes

just to work better in your body,

which is kind of like an unswitch.

So, you have the cruciferous family of vegetables

and you also have the allium, which is the garlic and onion.

Now, if you do the cruciferous sprouts,

like broccoli sprouts that are very high in sulfurophane,

that would be a really big trigger.

You can also do a supplement called Dim,

which is a concentrated form of cruciferous,

which is a potent stimulator of phase one,

phase two detoxification as well.

Now, the other really cool thing, which is pretty inexpensive,

is you just do fasting.

Fasting is a potent stimulator of the phase one,

phase two detoxification.

You wouldn't think that fasting could do that,

but when you don't eat, you start to detoxify in a good way.

And it's pretty inexpensive.

Now, number three, the obvious one is reduce the exposure

of these chemicals and toxins and poisons

and get with your doctor.

And maybe there's alternative versions

of some of the medications that you're on

so you can take maybe natural versions of these medications.

And then, number four, is just strengthening your liver.

And one big way to do that is to get the fat out of the liver

and the way that I recommend to do that

is to get on a healthy version of the ketogenic diet, okay?

And then there's a really good supplement called Milk Thistle.

You can take that, that strengthens the liver.

And then there's also herbal things that you can take,

curcumin, green tea, and garlic,

like I mentioned with the allium vegetables.

And for more information and how to target the liver directly

and get that fat out the liver,

I should really check out this video right here.

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