I Spent $2M Testing Foods. This Oil Cut Inflammation 85% (With Proof)

0:00This episode is brought to you by Google Chrome. You think you know a browser, but Gemini and Chrome? That's new. It can help you with practically anything on the web, like restoring a vintage motorcycle from a 50-page restoration block, or finally break down that long article you've had open for weeks. Gemini and Chrome is here for it. Ready to make anything online makes sense? There's no place like Chrome. Check responses set up require compatibility and availability varies 18 plus. When you need to build up your team to handle the growing chaos at work, use Indeed Sponsored Jobs. It gives your job posts the boost it needs to be seen and helps reach people with the right skills, certifications, and more. Spend less time searching and more time actually interviewing candidates who check all your boxes. Listeners of this show will get a $75 sponsor job credit at ND.com slash podcast. That's ND.com slash podcast, terms and conditions apply. Need a hiring hero? This is a job for Indeed Sponsored Jobs. Visible puts unlimited 5G data and hotspot in the palm of your hand, powered by Verizon's 5G network,

1:03with no contract holding you back. And for a limited time, you can get visible for just $19 a month for 12 months when you use promo code Save6. All the features of Big Wireless Service for half the cost. Tap the banner to switch today. Terms apply, standard rate applies at month 13, see visible.com for plan features and network management details. So a tech entrepreneur just spent $2 million trying to reverse his biological age. And honestly, the results are pretty wild. Brian Johnson claims he's reduced his inflammation by 85% using specific oils. And he says certain foods have literally turned back his biological clock. Now, I know what you're thinking. Another rich guy with a crazy health obsession. But, so a tech entrepreneur just spent $2 million trying to reverse his biological age. And honestly, the results are pretty wild. Brian Johnson claims he's reduced his inflammation by 85% using specific oils. And he says certain foods have literally turned back his biological clock. Now, I know what you're thinking. Another rich guy with a crazy health obsession.

2:05But, here's the thing that caught my attention. Johnson isn't just throwing money at random supplements and hoping for the best. He's tracking 67 different biomarkers every month and he's publishing the data. And some of his findings are actually practical for the rest of us who don't have millions to spend on longevity. So, here's the thing that caught my attention. Johnson isn't just throwing money at random supplements and hoping for the best. He's tracking 67 different biomarkers every month and he's publishing the data. And some of his findings are actually practical for the rest of us who don't have millions to spend on longevity. So, here's the thing that caught my attention. Johnson isn't just throwing money at random supplements and hoping for the best. He's tracking 67 different biomarkers every month and he's publishing the data and some of his findings are actually practical for the rest of us who don't have millions to spend on longevity. So, I wanted to dig into this because there's a real question here. When someone goes to these extreme lengths actually measures everything. What can we learn from it? What's real science and what's just expensive placebo effect? The basic claim is pretty bold. Johnson says he's reversed his biological age from 47 down to the equivalent of an 18-year-old in key markers, and he's narrowed down to specific foods and oils that he thinks are doing the heavy lifting. I wanted to dig into this because there's

3:09a real question here. When someone goes to these extreme lengths and actually measures everything, what can we learn from it? What's real science and what's just expensive placebo effect? The basic claim is pretty bold. Johnson says he's reversed his biological age from 47 down to the equivalent of an 18-year-old in key markers, and he's narrowed down to specific foods and oils that he thinks are doing the heavy lifting. I wanted to dig into this because there's a real question here. When someone goes to these extreme lengths and actually measures everything, what can we learn from it? What's real science and what's just expensive placebo effect? The basic claim is pretty bold. Johnson says he's reversed his biological age from 47 down to the equivalent of an 18-year-old in key markers, and he's narrowed down to specific foods and oils that he thinks are doing the heavy lifting. The guy eats exactly 1,977 calories every day and every single nutrient is tracked. His entire day is scheduled down to the minute, including bedtime, at 8.30 pm every night. So, let's start with the big question. Is this actually working, or is this just an expensive way to feel like you're cheating death? And more importantly, what specific foods and oils is he talking about? And could any

4:12of this possibly work for normal people with normal budgets? The guy eats exactly 1,977 calories every day and every single nutrient is tracked. His entire day is scheduled down to the minute, including bedtime, at 8.30 pm every night. So, let's start with the big question. Is this actually working, or is this just an expensive way to feel like you're cheating death? And more importantly, what specific foods and oils is he talking about? And could any of this possibly work for normal people with normal budgets? When you look at Johnson's actual protocol, the first thing that stands out is just how extreme it is. We're talking about someone who has turned eating into a science experiment. His morning routine includes this green drink with 11 specific ingredients, collagen peptides, creatine, and a bunch of other stuff that most people have never heard of. But here's what's interesting. He's not just randomly picking these ingredients. When you look at Johnson's actual protocol, the first thing that stands out is just how extreme it is. We're talking about someone who has turned eating into a science experiment. His morning routine includes this green drink with 11 specific ingredients, collagen peptides, creatine, and a bunch of other stuff that most people have never heard of. But here's what's interesting. He's not just randomly

5:15picking these ingredients. Each one is tied to specific biomarkers he's trying to optimize. So, let's break down what he claims is actually working. The inflammation reduction thing, 85% is a huge number. What oils is he talking about, and how is he measuring this? From what I can tell, he's focused heavily on specific types of olive oil and other anti-inflammatory oils. Each one is tied to specific biomarkers he's trying to optimize. So, let's break down what he claims is actually working. The inflammation reduction thing, 85% is a huge number. What oils is he talking about, and how is he measuring this? From what I can tell, he's focused heavily on specific types of olive oil and other anti-inflammatory oils. And he's not just saying, I feel better. He's running blood tests that measure inflammatory markers like sea reactive protein and interleukin levels. But, here's where it gets really interesting. Johnson didn't just change what he eats, he completely restructured when he eats. His dinner is consumed before 11am. Yeah, you heard that right. He's doing this extreme time restricted eating where his entire food intake happens in a really narrow window. And he's not just saying, I feel better. He's running blood tests that measure inflammatory

6:17markers like sea reactive protein and interleukin levels. But, here's where it gets really interesting. Johnson didn't just change what he eats, he completely restructured when he eats. His dinner is consumed before 11am. Yeah, you heard that right. He's doing this extreme time restricted eating where his entire food intake happens in a really narrow window. And when he start looking into the research on meal timing and inflammation, there's actually some solid signs backing up the idea that when you eat might be almost as important as what you eat. The question is how much of his results come from the specific foods, how much comes from the timing, and how much is just the fact that he's eliminated literally everything else from his diet that could cause problems. And when you start looking into the research on meal timing and inflammation, there's actually some solid signs backing up the idea that when you eat might be almost as important as what you eat. The question is how much of his results come from the specific foods, how much comes from the timing, and how much is just the fact that he's eliminated literally everything else from his diet that could cause problems. Because when you're eating the same measured meal every single day, you basically turn yourself into a controlled experiment. And that raises another question, what about the stuff he's

7:21not eating? Johnson has eliminated pretty much everything that we know causes inflammation, no processed food, no sugar, no alcohol, very limited variety. So, because when you're eating the same measured meal every single day, you basically turn yourself into a controlled experiment. And that raises another question, what about the stuff he's not eating? Johnson has eliminated pretty much everything that we know causes inflammation, no processed food, no sugar, no alcohol, very limited variety. So, when he says a specific oil reduced his inflammation by 85%, is it really the oil or is it the fact that he stopped eating everything else? This is where it gets tricky to separate cause and effect. Johnson's approach is so full that it's almost impossible to know which specific interventions are actually moving the needle. But that might also be the point. Maybe the real insight isn't about finding one magic food or oil. Maybe it's about the systematic approach. When he says a specific oil reduced his inflammation by 85%, is it really the oil or is it the fact that he stopped eating everything else? This is where it gets tricky to separate cause and effect. Johnson's approach is so full that it's almost impossible to know which specific interventions are actually

8:25moving the needle. But that might also be the point. Maybe the real insight isn't about finding one magic food or oil. Maybe it's about the systematic approach. Let me give you an example of how detailed this gets. Johnson tracks his sleep down to the minute and he's correlated his inflammatory markers with sleep quality, meal timing, and specific foods. So, when he sees his inflammation markers drop after introducing a particular oil, he can look at all the other variables and see if anything else changed. And let me give you an example of how detailed this gets. Johnson tracks his sleep down to the minute and he's correlated his inflammatory markers with sleep quality, meal timing, and specific foods. So, when he sees his inflammation markers drop after introducing a particular oil, he can look at all the other variables and see if anything else changed. And here's what surprised me when I dug into this. Some of his findings actually align with what we're seeing in mainstream longevity research. There's this study from Tuss Medical Center that analyzed over 400 metabolites from about 5,000 people aged 18 to 110. And they found that plant-based food, especially things like mush. This episode is brought to you by Google Chrome. You think you know

9:29a browser, but Gemini and Chrome, that's new. It can help you with practically anything on the web, like restoring a vintage motorcycle from a 50-page restoration block, or finally break down that long article you've had open for weeks. Gemini and Chrome is here for it. Ready to make anything online makes sense? There's no place like Chrome. Check responses set up require compatibility and availability vary 18 plus. When you need to build up your team to handle the growing chaos at work, use Indeed Sponsored Jobs. It gives your job post the boost it needs to be seen, and helps reach people with the right skills, certifications, and more. Spend less time searching and more time actually interviewing candidates who check all your boxes. Listeners of this show will get a $75 sponsor job credit at and D.com slash podcast. That's indeed.com slash podcast, terms and conditions apply. Need a hiring hero? This is a job for Indeed Sponsored Jobs. Visible puts unlimited 5G data in hotspot in the palm of your hand, powered by Verizon's 5G network, with no contract holding you back. And for a limited time, you can get visible for just

10:32$19 a month for 12 months when you use promo code Save Six. All the features of Big Wireless Service for half the cost. Tap the banner to switch today. Terms apply, standard rate applies at month 13, seevisible.com for plan features and network management details. Frames that contain compounds like kergothioneen show up consistently in the metabolites of people who live the longest. Here's what surprised me when I dug into this. Some of his findings actually align with what we're seeing in mainstream longevity research. There's this study from Tuss Medical Center that analyzed over 400 metabolites from about 5,000 people aged 18 to 110. And they found that plant-based food, especially things like mushrooms that contain compounds like kergothioneen, show up consistently in the metabolites of people who live the longest. Johnson's daily protocol includes a lot of these same compounds. So, WH Con takes an extreme approach. He might be on to something. The question is whether you need to go to his level of obsession to get meaningful results. But, let's talk about the critics for a minute because there are plenty of them. Johnson's daily protocol includes a lot of these same compounds. So, WH Con takes an extreme

11:34he might be on to something. The question is whether you need to go to his level of obsession to getting meaningful results. But, let's talk about the critics for a minute because there are plenty of them. The main argument against Johnson's approach is that it's basically impossible to replicate in normal life, and some experts worry that this level of restriction might actually be counterproductive. Dr. Davidson Claire, who's pretty well respected in longevity research, said Johnson represents the extreme end of longevity intervention, but some of his protocols align with what works in lab studies. The skeptics point out a few things that are worth considering. The main argument against Johnson's approach is that it's basically impossible to replicate in normal life, and some experts worry that this level of restriction might actually be counterproductive. Dr. Davidson Claire, who's pretty well respected in longevity research, said Johnson represents the extreme end of longevity intervention, but some of his protocols align with what works in lab studies. The skeptics point out a few things that are worth considering. First, Johnson is essentially an experiment of one, just because something works for him doesn't mean it'll work for everyone else. Second, the level of control he maintains over his

12:34environment is so extreme, that it's hard to know what normal people could actually implement. And third, there's a question about whether living like a perfectly optimized machine is actually a life worth living. There's also this interesting point about the psychology of extreme protocols. First, Johnson is essentially an experiment of one, just because something works for him doesn't mean it'll work for everyone else. Second, the level of control he maintains over his environment is so extreme, that it's hard to know what normal people could actually implement. And third, there's a question about whether living like a perfectly optimized machine is actually a life worth living. There's also this interesting point about the psychology of extreme protocols. When someone spends $2 million on something and dedicates their entire life to it, there's a huge incentive to see positive results, even if they're not really there. Johnson publishes his biomarker data, which is great for transparency, but biomarkers don't always translate to real-world health outcomes. And here's something that made me pause, there's recent research showing that long-term supplementation with certain B vitamins, which are part of Johnson's protocol, actually increased cancer incidence and mortality in some older adults. So, even when you're trying to optimize everything, there can be unexpected downsides.

13:35But, the counterargument is that Johnson isn't just taking random supplements, he's adjusting based on continuous feedback from his biomarkers. If something isn't working or causing problems, he can theoretically catch it and adjust. The question is whether that level of monitoring is worth it, and whether it's even possible for most people. There's also this broader question about what we mean by keeping you young. Johnson's biological age markers might show improvement, but what about quality of life? What about spontaneity, social eating, enjoying food for pleasure rather than just fuel? These are trade-offs that his data doesn't capture. Looking at this from a practical standpoint, what can regular people actually take from Johnson's experiment? Well, there are a few things that seem promising without requiring a complete lifestyle overhaul. The time restricted eating thing is something anyone can try. The focus on anti-inflammatory foods, especially certain oils and plant-based compounds, is backed by research that goes beyond just Johnson's experience. And here's something interesting. Johnson's dream Mediterranean-style diet approach actually aligns with recent research showing that this type of eating pattern slowed aging on 10 out of 16 epigenetic clocks in clinical studies. So, while his

14:37execution is extreme, the basic framework isn't crazy. The specific oils he talks about for inflammation, high quality olive oil, certain omega-3 sources, these are things that normal people can incorporate without turning their entire life into a science experiment. And the meal timing aspect, even if you can't eat dinner before 11am, like Johnson does, there's good evidence that giving your digestive system longer, breaks between meals, can reduce inflammation, but here's what I think is the most important takeaway. Johnson's approach works because of the systematic nature of it, not because of any single magic food or oil. He's eliminated variables, he's measuring results, and he's making adjustments based on data. Most of us can't replicate his exact protocol, but we can borrow the approach of being more systematic about our health choices. If you had to take one practical thing from all this, I'd say it's the idea of treating your health like an experiment. You don't need to spend millions or track 67 biomarkers, but you can try eliminating inflammatory foods for a month and see how you feel. You can experiment with meal timing, you can be more intentional about the oils and fats you consume. The question isn't really whether Johnson's specific claims about reducing inflammation by 85% are replicable. It's whether his systematic

15:42approach to health optimization contains insights that can work at a more reasonable level of commitment and cost if you're curious about practical longevity strategies that don't require living like a monk or spending millions. We've got some episodes coming up that explore evidence-based approaches to healthy aging that actual humans can stick to. So, here's what I keep coming back to with Brian Johnson's experiment. Yes, he's probably onto something with the anti-inflammatory oils and a meal timing. The biomarker improvements seem real and some of his findings align with broader longevity research. But, there's this deeper question about what we're optimizing for. Johnson has essentially turned himself into a perfectly calibrated machine, and that machine appears to be aging more slowly than the rest of us. But, is that actually living or is it just existing more efficiently? Maybe the answer is somewhere in between, taking the insights that makes sense like being more intentional about inflammatory foods and meal timing without sacrificing everything that makes life enjoyable. Because what good is living to 120 if you spend every minute of it, measuring and optimizing, instead of actually experiencing life. Thanks for listening.

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