Let’s talk Ozempic...again! [Waterbreak]

0:00This shows brought to you by Kings Ridge Elderberry Farm. Visit tkr farm.com. That's King the Kings Ridge Farm, tkr farm.com. And purchase your elderberry needs from the Kings Ridge Elderberries. Use code WB10, that's waterbreak WB10 for 10% off of your first order. And as kind of a personal antidote here, me and my wife have used this elderberry cocktail that they make is fantastic. And our kids love it. In fact, our kids are putting it in yogurt and all sorts of things. And we've had other flavors before that we not liked in this. And the cocktail that they put together for the elderberry juice is fantastic. Go to tkr farm.com and support them. Now y'all welcome to Waterbreak. It's good to be with you on the FireLaf East Network. It is already fall here September, fall is hitting 60 degree weather. That kind of thing. But for today for our show, we're going to be talking about the olympic round two.

1:01And what we mean by that is last year we talked about olympic and of our first shot at the top of the olympic. Well, we're going to hit round two with you guys today. And before we get there, make sure you guys go to fightlifevice.com. Sign up for our conference. We're going to be out in Tennessee literally just in a month. So go to fightlifevice.com. We've got our holy war conference happening there. We've got a pre-business conference on Thursday afternoon. Beer and Psalms kicking off Thursday night. And then of course we end the conference of the live show, cross-phalty live show on Saturday afternoon. So, love to see you guys out in Franklin, Tennessee. Nice area of Franklin, Tennessee. The factoring in Franklin is where we're going to be out and everything. So that's all the announcements I have. Do you have any announcements before we get started? I rarely have a notice list. Now you're done. That's my job. You do all the talking and then I work a little bit. So, a zimpik round two, baby. Why did you want to kind of want to hit this topic now?

2:03We covered a year ago. I can't even remember what we covered a year ago on this. I remember the show was it had great feedback. So actually, if you guys are just new to us, listening to us on this show, go actually find the exemptic round one. You should. It was almost exactly a year ago. It was August. I went back to that. Where we talked about it was that big. It was a good show. We got a lot of feedback on it. It's what I remember. We got a ton of feedback and understandably so because it's such a big topic right now. I don't think there is a bigger movement trend in the health and fitness health, I guess, space. Then these GLP1 agonist drugs, like I don't think there's anything bigger. So, if you look it up, if you just Google it, it will tell you that one in five women are on it or have used it at this point. But I would not be surprised you guys. It's like depression medication. Yeah, right. Or the birth control pill. This reminds me of the birth control pill. But possibly it does more damage. I'm not sure.

3:04So I'm going to interrupt you how you want to start your notes. Because I think it might be helpful to remind our listeners. Like, what is a GLP? Like, chemically, what is it doing? You know, that kind of thing. Yes, so that's a great idea and we can do that. So I'll let you say these drugs are a really big deal. Like I just said, according to Google one in five women are on it. I would not be surprised if it's more like one in four, one in three. Because these are under reporting. A lot of people are also not saying that they're on it. They're being honest. Whatever, I understand. Yeah, I'm working out. I started working out. Yeah, like the Kardashians. I've just been eating a lot of fiber. So I'm guessing it's more like at least one in four. So it is super prevalent. Doctors are prescribing them very heavy handedly. They're becoming fat like quickly, almost just normalized. As just what you do to lose weight and be healthy. It's getting lumped into BHRT bioidentical hormone replacement, which we can get to that. I do not agree with that happening. But it's happening. So it bears talking about again.

4:07And these drugs have been, I mean, even when we talked about it last year, they'd already been circulating in the general population for a year or two. I kind of put off talking about it. But, you know, no, you guys, it's here. They're here. They're probably here to stay. And it's a year later. So we have more, we have more thoughts. I want to revisit it, you know, because it's still super relevant. So great point. Really quick. You can go back to our last show. It was in August of last year. It's titled The One Where We Talk About Ozepix. So it's hard to miss. That's, we just sort of talked about what they were and just bullet proved through different thoughts about them. So it is a pretty, I think it was a good show. We got a ton of feedback from you guys. So we're not going to repeat that this time. I want to kind of hit it from some different angles. And obviously they've been in circulating amongst the general population for longer now. So we have more to talk about. But what are they? Basically, I'm just saying ozepic because that's maybe the most famous brand name for some of Glutide. Okay.

5:07But it was the general one of the first generation, what we call GLP1 agonist. So basically, GLP1 is one of your Inkerton hormones. You have GLP, GIP. They are secreted in the gut after you eat and they help immensely with feeling full and slow and gastric emptying, etc. So some of Glutide is the generic name of the drugs like ozempic, wagobi, probably be familiar with those. Those are sort of the first gen drugs that came out. Those just work on GLP1. Then we've got the second wave, the dual agonist that work on GLP1 and GIP. That's going to be your teazepotine in those go by the names of mongaro, Zetbaum. There's others, but those are probably the most popular. And there's a third one coming out. It hasn't been FDA approved yet. Although people are already using it through research labs, etc. And that's red, a true tide. That will be a triple agonist that works on GLP, GIP and Glutidon. Now, that's a little nerdy. You can.

6:07And so I guess practically what is it doing? Yeah, I'm going to get to that. But I'll let to say there's different generations of drugs, but you can generally lump them all together, per this discussion, mostly used for weight loss in diabetes. That's what they originally designed for us for diabetes. Understandably, because they work very well to bring in fast and insulin down to bring glucose down to bring things back and range that do work very well. So just in terms, you just. So I practically make himically what is it doing exactly these are agonist drugs. Okay, so they are there are synthetic drug made in a lab that are designed to go into your body and attach to a receptor. The receptors for the things we just talked about the in curtains, your GLP, your GIP. And basically crank on that receptor at a very, very high level so that that GLP GIP is being elevated or you know, produced or the effects of it are very high all the time. So that's what they do. And so you're getting the effects of again, way less hunger. A lot of people it's low grade nausea that comes along with it slower gastric emptying.

7:10It also works on the brain. There's a brain gut connection. So overall, you're not as hungry. You don't eat as much food. It's also quite effective. Like I said, at working kind of as an anti diabetic diabetic drug where it produces more insulin, brings blood sugar into a healthy range. So they're quite effective in terms of what they're supposed to do. They're quite effective. Does that sound good? I mean, that's what they are. Yeah. And is it like it's suppressing your hunger? Big time. And then is it doing also something to like your thyroid or something? I thought there was like something else that was happening. No, I mean, not directly, but it is it's affecting your pancreas because it's affecting it's pushing out insulin, et cetera. It works on a lot of things, but the main things that people need to understand is that it does work to help lessen the, you know, the effects of diabetes. And it greatly, greatly reduces hunger and what people would call food noise when they're just thinking about food. And I guess that's what I'm getting at is I had a friend, I mean, overweight for a long time. You know, health, health deteriorating and his doctor said and he's in this health deteriorating where he was starting to get diabetes.

8:15Yeah. Because of right. And his doctor's like, hey, you're your perfect candidate for GLP, you know, for Zimba, whatever he's on. He said, you're a good candidate for it. And so he started taking it and he obviously he did lose his weight, but he's also his diabetes went away. Yeah, totally. Yes. Yeah, it actually does work. And that was what it was designed for. I mean, the weight loss thing is kind of like a fun side effect, you know, but like really these were designed for diet for diabetes. Really? Yes. Very well. I would have be very clear about that. They work very well. They're next level from things like burberry or metform and they're more effective. So, yeah, 100%. So, you know, all that to say these drugs are they're everywhere. They're mainstream. Everyone's on them. A lot of people are on them and they don't really understand the mechanism of them. What the long term like fallout might be. And that that's a little scary. So that's one of the reasons I want to keep talking about this because I feel like they're being touted as sort of a magical till where there's like zero downside, you know what I mean? And who doesn't want some weight loss?

9:16Obviously, you know, and weight loss can be very hard. Without trying. Yeah, well, yeah. And I mean, that's what's so special about these is that there's been all these other things like being keto, being carnivore fasting, all these other things where yes, they can't, they're very, they can be very extreme. You can take them very extreme. They can be effective to a point. But what always gets you in the end, it's hunger, right? That's what sabotages every diet attempt, especially extreme diet attempt where you're restricting by any name. Hunger gets you, right? These drugs, that's what's so unique about them is that it kills your hunger, especially if you're on a decent dose so that you can effectively start yourself. And that that's what's unique about them. That's the draw. And that's how we're seeing not in everybody who's on them, but we are seeing emaciated bodies walking around. We are seeing people who are absolutely like skin and bones. We're seeing that in Hollywood. It's crazy. It's crazy what we're seeing. And that look is very hard to achieve unless you are on a drug like this or you're dying from cancer.

10:20I mean, it's really hard to get there. So it's, it's an interesting time that we're in. Okay. So now that we've kind of defined what they are, basically what they do. And I know if you're, if you're a doctor, you're somebody who's really sciencey. I know that these drugs do other things beyond what I just mentioned, but it's enough. I think to cover what we're talking about in this conversation. Well, and the majority out there is not using it for all these other things. 100% 100% people are in it for the weight loss or they're looking a little prediabetic in their blood work and the doctors like, well, this will help. Right. So the first thing I want to talk about this, this time around, because again, I don't want to just do a repeat of last time. Is I want to first talk about why does everybody feel like they need to be on this in the first place? Like why are one in five women, maybe one in four, maybe one in three? We don't know on one of these to begin with, right? Because you don't usually go on a drug for no reason. Like, like usually there's a reason, especially one like this that is heavy hitting. It is there are major side effects in both the short and the long. And we discussed those in our last episode. You can go back and listen. They're expensive.

11:21So it's like, why are we all feeling like we need to be on this in the first place? Because I think that's a really good question when you see a huge fat or a huge movement. It's not, I don't want to just address what I think about the drug. It's like, why are we all on it anyways? Okay. So the first reason it can be the obvious one. And this isn't true of everybody. But I think we need to acknowledge that there is a very American tendency to want to just jump on the next quick fix bandwagon. And we've all done it. I mean, a lot of us women have done this for years. We jumped on the adkins and then the keto and then the whatever. Like, you know, whatever the next crazy is like, oh, is this how I'm going to get thinner? Oh, is this how I lose 10 pounds? Is this what we're all doing? And we just jump on it and we often do it without a very much understanding of our own physiology without understanding how metabolism works long term. That's for sure. And just without thinking long term in general, we just like a quick fix. Like, I want to be skinny now. I want to be thinner now. I'm getting this isn't everybody. But this is a thing. And I think again, these drugs, these JLP, GIP, Agonist drugs are being peddled and presented to people like they are sort of just a magic pill with no downside.

12:31And I think that's really dangerous very much like the birth control pill has been presented to young women for years where there's just no conversation. No, no, no downside. No informed consent about what some of the long term fallout very well might be. You know, so it's it's something to think about. I just want to note this. I mean, I did make an Instagram post about some of these things a little while ago. And so I thought it through. I've been thinking about it for a while. But so many of you guys who are on this drug. And I want you guys to note that these drugs are designed to be taken for life. And that's because they only work when you're on them. And it is so important that you guys understand that. And I think that's true of most drugs. But it's very true of these ones. If you understand the mechanism of them, once you take them away, they stop working. Okay. What was I going to say? Oh, a lot of you are on these drugs just like, yes, give me it. Wait, when you back in the COVID day and everybody was pushing the vaccine, you rejected the vaccine due to the fact that there was not enough study done on it and it was experimental.

13:31Right. And it was and you were right to be skeptical of that vaccine and be like, listen, listen, I don't want to be a human experiment. But I don't I don't know how many of you who have said yes to these gel be ones. I have the same skepticism. I really looked into it very much because if you had, you would find on the black box, you must take these for life. Why? Because they only work when you're on them. Everyone knows this. The makers of the drug knows this, the doc, anyone who knows what they're doing knows this. That's why the design of it is you have to take these forever. Even though fun fact, we the longest study we have on these is seven years. So do that math. You start this when you're 40. 47. I mean, that's a big risk you're taking. And I think it's funny that we all were like, um, COVID vaccine, but, but a lot of y'all jumped right on this. I either not thinking about the fact that this will stop working when you get off it or end or you have to take it forever. I, I, it's something to think about. Okay. Um, another reason why so many of us feel the need to get on a GLP one right now is because years.

14:34And I mean years of not managing root cause health drivers has caught up to you. And, and this I would say covers probably the majority of people, um, who are on this because things do in midlife get real bad and real hard. Like that part is true. Um, but there's a reason for that. And it's unfortunate because hindsight is 2020, you know, and you can't, you wish you could go back in time and change your behaviors in your habits, but you can't. But if you, if you do not prioritize early on good nutrition, intelligent and impactful exercise, prioritizing sleep and managing stress. You don't do that. And those boxes are not checked. The negatives of them compound over time. It does not stay the same amount bad over time. It compounds and it compounds in it compounds. So if you start treating your body like trash when you're 20 by the time you're 45, you can be in a really bad spot.

15:35And I know this to be true. These are the kinds of people that I work with all the time, right? So it's not like you're lying when you say, oh, my health is bad. My metabolic rate is low. Nothing is working. You're right. But the reason, and I think it's important for us to acknowledge this, the reason a lot of us got there is because we ignored all of these root cause health drivers. And we did not prioritize them. So that's one of the reasons we started the show is to talk about these things so that we can all start ideally early. I guess it's better late than never. You start wherever you are. But you have to be mindful of good nutrition, your exercise, your movement, your sleep and your stress management. We have to. We have to. It's either going to improve slowly over time or it's going to get worse and worse over time. And again, by the time you hit midlife, if these things have been ignored, and I would say the average American does ignore them. They ignore them and or don't prioritize them. Not oftentimes because you're lazy, but because you're busy and you have built a life that does not think that those things are important enough for them to have a place. We just haven't built lives like that.

16:35And it's like all fun and games until you hit midlife and you are insulin resistant or you have other major health issues, your sleep apnea, your blood pressure, all the things that everybody has, flat landed renales, a poor hormonal profile just in general, disregulated hunger hormones for sure, low muscle mass, etc. Again, like a lot of us are in a pickle because we did not start prioritizing these things a long time ago. Okay. Another one and this would probably this could kind of, it is included in the one that we just said, but it gets its own category because it's so common. And that's years of under eating or yo-yo dieting. This applies more to women than men, but there are so many women who have been dieting either constantly or on and off for 20 years. And you do that. If you do that, you can down regulate so hard. And you can find yourself in a spot. And again, these women come find me. So I know they're out there. I've worked with them. Like you can get yourself in a spot by the time you're 40, 45, whatever it is, where you really are only eating a thousand calories a day.

17:38And you cannot lose weight. Maybe you're even overweight. Your body has just down regulated slowly over time. You can talk about this phenomenon all the time, but you really can get yourself there. And years of just being obsessed with eating less, waist-eat-less, the number on the scale as opposed to actually what is health. Like what do I need to do to be healthy because you'd be taken a hold of for an approach if that was the case. And just eating less and less and less and less over time. And maybe you fall off the wagon in between. Usually you do because the body fights back. You can end up with a very, very down regulated metabolic rate of very slow thyroid that usually comes along with it. And you can be in a place where you're just absolutely desperate. You're just like, nothing is working for me. I am barely eating the only answer. And I said this on our last show is usually either super aggressive fasting, which is usually what people try first because it's free. Or one of these JLP ones. I'll tell you right now that is the absolute last thing that you should do if you're in this place. What you need is a reverse diet. Look me up. I'm happy to work with you and help you through that. But you need to eat more.

18:38You do not need to take a drug or start fasting or do anything that's going to cause you to eat less. But all that to say, a lot of you are there. You're in that really bad spot of being super, super metabolically down regulated because you have been eating so little for so long. And remember, this is how our bodies survive. Like the our bodies are super adaptive up until now in history, having food all the time in abundance wasn't really a thing, you know, like until kind of recently. So like this is how our bodies survived for years. They could adapt if food wasn't there. They're like, no problem. We're not going to be doing great. But we're not going to die. We're just going to down regulate. Right. That's what you did during famine. That's what you did if you were poor. That's what you did. And that this is how people survived. But it's it's a little inconvenient here now in 2026, especially if you don't understand how metabolism works. Okay, here's a big one and gave I know you've got something to share with us on this one here. This isn't reason number four. Why I think so many women are finding themselves on a gel P1. And that is because we do not understand women's hormonal health.

19:39At all doctors don't understand it. We don't understand it. Women are medically gaslit. It's getting better at the starting to get better. But it has been a huge problem. And I my guess is if you know half of the women at least who are currently feeling like I have to get on gel P1. Nothing else is working for me. Actually had their thyroid optimize had their testosterone, their progesterone, their estrogen all looked at replaced as needed and everything tuned up to where it needed to be. They would not need a gel P1 and that actually makes me really, really sad. We have a tweet that we want to yeah, and just a tweet example that we want to give here. Just some kind of background comments. We said so many times on the show kind of gone through all the different factors that could really complicate not just you know men's health lack of sleep stuff like that. But also ladies health, which is just even more complicated. More so complicated. So to and and then like the medical doctor field has been so educated by the government.

20:48The food pyramid, all this stuff is coming from one perspective. It's it's kind of closed off a whole other way of not whole other way of thinking but just a broader way of thinking about especially women's health when it comes to women's health. And so you know you're going when you go to a doctor, you're getting a very defined experience that should you know I think it needs to be broader but it's just been the culture of how we've educated our doctors that have really kind of put us in the situation where it's like you've got to go find like an alternative doctor that's going to be willing to look at your whole blood panel and just not like this this and that you know. And so but part of this is also just created like this this bucket of like you know hate to hate the word but like misinformation or or or information that only is like part of the picture that ends up being unhelpful.

21:51And especially I think in a lot of ways to kind of women's health right now. Yeah, you got him and again, the men's health got some complicated factors but like it's just whatever multiplied with you guys God multiplied it. Yeah, we have challenges we have more going on and so like there's this I think something that kind of captured it for me a couple weeks ago there's this tweet that came out and I don't I want to stay away from the drama and all this stuff but basically this is a tweet saying I regret to inform you that you're if you're fat you can just lose weight. Nobody can stop you but you it's not actually super complicated and has very little to do with hormones or your thyroid or your metabolism or whatever else you've been scapegoating I'm sorry. And that statement I mean like in some sense you could just not eat and starve yourself to death and your hair falls out and you slowly you know don't eat for 30 days and see what happens you know you're eat 500 calories for 30 days. True if you take it to the extreme. Yeah, you can you know and but the reality is actually because we're heart solemine and because our our bodies are you know wonderfully made and but we're in a fallen world and so the intricacies of what goes in our body.

23:07Need to be met at an individual level I mean that's how that's what it means to be any that's what it means to be gay that's what it means to be you know whoever it's like you're a unique person made in the image of God and you're going to have unique challenges also as part of that in a fallen world. And so that's why you know I think any talk can you talk about the very beginning of the show is like like in some sense like we've been gaslit with our health I mean like I know this has been you know. You know I mean we go back to there's some easy funny things you know we've been gaslit with our health the food pyramid was a joke. You know you remember the old the old commercials we should go and do this we did this on it we did a show a long time ago probably like in our first 10 shows. And I walked you through all these like ads. Oh yeah it was funny. It's just kind of more of a funny show or just talking about like the doctor recommended you know Virginia Slim's the most or something like that. Dr. Rickman. Dr. you know so you got this like culture of medical field that has added to the problem and then you got additional kind of you know tweets like this where it's just like.

24:17Yeah there might be a ounce of it true but it's actually you're actually doing more harm than good because there's actually a lot of women out there who need to reverse diet go check out our shows on reverse dieting. Yeah there's a lot of you know there's been so much harm in yo yo dieting all these dieting for women for 40 years and it's no wonder there are 45 years old now and 30 pounds overweight but they've been dieting their whole life I mean talk about like I know eating less the whole life they've been doing this they've been doing this for 30 years and now they're in a really bad spot that I really thought that irony and so if your metabolism is not functioning well you got to figure out how to jumpstart it how to get a going in or you know there's this you know so this this kind of tweet you're I know your doctor saying the same thing that's why we're that's why we're just bringing this to you to his example I know your doctor saying the same thing and and you're you're starting to feel like you're crazy because like man I'm now down at 800 calories and how much less can I eat yeah I can't eat in your life

25:22are you doing oh Matt what else can I do and and so your doctor's like well maybe add oatmeal to your diet or something or my favorite yeah or maybe do this or whatever and you're like I'm starving I'm gaining I can't lose weight and then you know and then that's why it's like looking at your heart's will mind like this is why on on water break we talk a lot about like we want you to think in the way God thinks about your body we want you to think the way God thinks about your life your your your your maiden his image your way more complicated there's a lot more going on and so you know that's why any sometimes like I remember when any first or talking about like you know I need to get more sleep I remember years ago you started getting more sleep and and you know my bed habits are gotten you have gotten a lot closer to years but she would go to bed at you know let's say 9 30 10 at night and I'm it's 11 o'clock by the time I can fall asleep because that's just the habits and patterns I've formed over the years but then Annie's health started getting more actually as she got more sleep and did some other things too along with them

26:24just pinning on sleep but this is big one as she started getting more sleep I mean I remember she went through this time like where her hair was falling out in this years not just time where your hair was falling out your hands were constantly cold yeah that was yeah and just some just some funny kind of sick all the time yeah yeah knows running you know this kind of time we always I always kind of poked at her a little bit how healthy I was and how much she worked out and how much I didn't work out and how healthy I was really sick and she was I probably three sign is in fact and bait major sign is infections a year I haven't had one years no you have one years long time but yeah she she'd squirt her nose because she's literally getting three or four sign inspections every year so it's a dark time you know we're happy to talk about some of the details or health but like really the the point is is like like listening to kind of tweets or or really doctors who are just kind of being unhelpful in a way that's not looking at everything that God has given your body because there's real solutions besides just eating less

27:31like to simplify things to eating less yeah it's reductionist is very reductionist and also has created I think I think there's probably a lot of a lot of guys out there and a lot of women out there who just feel like well there's nothing else I can do and the reality is actually I mean Annie's worked with women before the reality is like sometimes it means you actually need to eat more eat more healthy and get more sleep and just some of these basic training like you know like you mean eat more and lose weight you know you mean you mean more sleep yeah I mean walking so these some of these things are I just wanted to kind of launch off that tweet because I just want to encourage you guys like there's there's actually without ozemic without some of these cheat drugs without some of these things that really is a better road for you in this so yeah well yes yes everything you said and this this tweet basically I'm just saying it kind of went on over that's why we're kind of talking about it yeah but this this tweet of course it makes me mad but this guy's not alone tons of people tons of people men in particular sound this way

28:35and you know I've said this before but one of the reasons it bothers me is that he's making the cardinal very childlike mistake of just assuming that what worked for him at one point in time will of course work for everybody and that is very very like you said reductionist and not true and all it takes you guys all it takes is being somebody in the business who has a basic handle on physiology metabolism and who has worked with a lot of people over a lot of time is soon as you start doing that you realize okay this works for you but the same thing did not work for you why is that okay and there's a lot of things that play in there okay gender is a big one all right what works for men a lot of the time does not work for women that's not because we're that different we are different but a lot of times it's because the one his body is more stressed out she's more hormonally walked out she already she started dieting 20 years ago and he didn't right the first time he tried to lose weight super

29:36easy what he says works just eat a little less move a little more my guess is I don't know the guy and my guess is probably first time he's ever done it and that's why it works so well but that is but then to make the very very like child like an arrogant assumption that that should work for everybody and they're stupid if they don't agree with you that's crazy and and it's one of the biggest issues in the business I don't even think this person is in the business which is even funnier because it's like don't talk about things I you know it's one of my things in life I try not to have opinions about the things I don't know about I think it's a good rule but even the people who are in the business so many of them make that same mistake they just assume whatever works for them or is even working for them right now you know should work for everybody and that is just not true okay now I will say this there is because hormones hormones such a broad term you know who knows what it means is is becoming more popular now we're kind of in the new wild wild west of it where everybody's like understanding acknowledged in them understanding their important trying to understand them better and that's good because of that they can get blamed sometimes where actually no you're just eating too much and not moving but you know what I mean and that's

30:39totally true you know I mean you can lots of things can be true at once okay but that does not discount the fact that I mean all this stuff a couple examples here well here let's use thyroid just just thyroid there's other hormones but I'll just use myself and again I'm not using myself and assuming this is true for everybody I work with a lot of people in the thyroid universe and I've seen this play out many many times what are you still under point four yes I'll use myself I right now I went I over a several year journey I had to hop from doctor to doctor I was kind of a complicated case it was kind of painful but I'll let you say my thyroid journey took me from a free T3 of 2.0 which is very low to where I am right now sitting around a 3.5 which is about where I like to be I am 15 pounds lighter than I was then and I am eating more food okay this is true I remember when you were eating that much and it bothered me that you were eating that much and yeah yeah yeah I was so down I was yeah I was full and sick and I was so tired do you remember we would even we almost fight about it like you

31:43weren't mean but you were just like why are you so tired and I was like I don't know so tired I just could not oh my goodness every day was just like this like white knuckle grind it was it was misery was funny about part of this is like it has been you're like you don't know your spot you don't know it is just how all women are like so tired all the time but like the tired phase of our life with our kids was over yeah right the tired face it didn't it didn't make sense it didn't make sense I'm like why are you tired or now then we were when our kids were 3.2 and 0 and I just remember being like I don't know what I don't know I just know that I am I'm dying and I was like Lord please forgive my little wife for her laziness complaining about me not like are my prayer for myself like when you would text me I mean I just you know you move on from phases of life and you sort of just forget it but like I can remembering it is crazy like you would be like how can I pray for you and I would old for years I would just be like energy yeah more than anything I should please pray that I have energy

32:47like I would just be so tired it's just crazy you guys that that is the power of the thyroid it's just an example it's funny to think about just for us because like there's a real phase there that it was it felt like we're like two ships passing in the night with your health oh gosh and you're tired and I'm just sad because it's like I wish I had figured this out so much it's okay yeah yeah but that's one of the reasons I'm so passionate about the thyroid in particular for women because they are running so low on so many people and it is not caught and really are just like I guess this is just how I am I'm just fat and constipated cold and exhausted and it's a terrible way to live and why live that way if it's actually quite an easy fix if you know what to look for and you work with someone good but anyways that's just thyroid there's other hormones to take into consideration you do see it when you hit when women hit pariametopause and menopause you see body fat increase often and and this is the weird one redistribution usually right into the middle right you end up with this belly that in some cases you never

33:49had before and that's due to dropping estradiol estradiol gives you insulin sensitivity and when you lose it women tend towards being more insulin resistant and that can happen when you have changed nothing another example because I am someone who understands that everybody is different and it's not just what's true for me is true for everybody else I have a client she is phenomenal she is and I would almost say elite level cyclist she is a phenomenal fit cyclist strength drinks twice a week is cycling road biking miles and miles and miles and miles every single day she moved you know got right into like you know 50 or so which is I think the average age for you know on average full menopause is 51 52 and she brought me her blood work and she was like look at this her glucose was high her facet insulin was high she she was like I also have this like belly now that I've never had before she's like my training is the same I'm probably sleeping even more than I did when I we know my kids were young and et cetera

34:53I nothing has changed and she is just horrified just like what is even happening and she's a really good example of now obviously if you're not taking care of your body not managing your stress eating crap this is even going to be worse it's a terrible time those are the women who have a terrible terrible time through pray menopause menopause so there is a lot that we can do this is a perfect example someone it's like she couldn't exercise anymore she couldn't eat me better like she's like super fit super active and I was just like well this is because you're losing estrogen and so we got her in with a good doc she started titrating up some HRT feels so much better numbers are back and range lost the tire around the middle like it really you guys it's a big factor another and I'm not going to be this list of hormones that can affect weight weight loss resistant et cetera this is not exhaustive there's a ton of things that can be going on but these are just the big ones big ones that I see so we just talked about with estridol dropping becoming more insulin resistant that's very real when progesterone goes you lose your sleep and that so that's an indirect way that you can really take your health I mean it is so hard to not gain weight and sometimes very rapidly when you're not sleeping your

35:59hunger hormones are whacked out your blood sugar goes up you can't think straight your workouts are like you're so it's so bad and so progesterone is super important also testosterone will go downhill that's huge for fat burn and your ability to build and maintain muscle which is really really big cortisol dysregulation huge the tends to be a very stressful time of life for women in general oftentimes you have older busy kids and maybe you're even getting into care taking for your parents it's a rough time and it's a time where you're more sensitive to stress than ever because your body's leaning on your adrenals to crank out some sex hormones as your ovaries are computing so it is not a good time for your adrenals and this can really add to weight loss resistance and the last thing I want to add is that another way that hormone fluctuation or hormones dropping can hurt your health is that and this was kind of like what we were just talking about with me in my really low thyroid time is that when you are that low energy and that brain fogged and that can happen

36:59as a combination of a lot of these dropping it's really hard to even fathom exercising it's really hard to even fathom meal planning or like cooking healthy food for yourself and your family like a lot of these women feel so bad and their energy is so low and they have no motivation and their brain isn't even working they can't even remember their kids names like look at that woman and be like yeah well you need to do this you need to go ahead and you need to start running every day just like you need to cook better food you need to you know it's super super hard so hormones are really important for that side of things too so that you so that you so you don't feel like garbage so that you can actually fathom taking care of your body and taking care of your health so you know I think this is a big one I think it's getting better but I think it's a big one and it makes me really sad how many women have felt desperate enough to get on a big one really this is what was going on so okay one more reason because we're still talking about all the different reasons why I think people are on GLP ones this is number five and this is the last one there's others I'm sure

38:00but these are the ones I wrote down is we talk about the bigger stronger bodies on this podcast a lot because I love you guys and I am cam McDonald calls and guardians so these are just bodies it can be men and women you can be a tall version or version but you're just naturally bigger and stronger you always have been you came out that way bigger bones usually you are very strong for your size you have no problem you have a lot of muscle you don't lose muscle very easily you like to squat build yeah I mean a lot power lifters throwers or just people were just strong like really strong you know you're usually like the strongest one I don't like this what the strongest one in the class and you're just thicker you're just a bigger thicker person modern health advice right now is so bad for you guys it is so bad like early morning stress eating a ton of protein it's so bad for you guys and also these bodies 10 towards being genetically they 10 towards being more insulin resistant as it is and when your bodies are under stress and who here isn't under stress you become even more insulin resistant and you hold on to

39:04weight you pack on weight that's just what your bodies do and it's kind of like you know from a historical standpoint you're the body that could could do that go without food and give your food to everyone else to all the little bird people who are wasting away so like what I mean and they tend to be you guys tend to be super loving super kind super caring pretty much the mental health of the earth and just miserable because you're you feel so bad and you can't figure your body out and every time you try keto or carnivore or 5 a.m. Crossfit you gain more protein you gain five more pounds and you get gout and your doctors like oh well your glucose went up and you're just like you know like completely like I have no idea nothing works for me I feel like a crazy person give me the GLP one you know and I I don't even know what to say to you guys I'm sorry like you've gotten you've been mistreated so badly doctors don't know what to tell you all the health and fitness advice is so bad for you guys I would still say a GLP one should be a last resort but you I completely understand why you're just

40:06like give me it like nothing else is working you know it's it's really really tough so I love working with you guys what you need is very different than what the other little bodies that tend to be fitness influencers need and I just yeah I love working with you guys and I'm sorry I'm sorry for all the bad advice and all the gaslighting that's been happening to you and I understand I understand why you would turn to a drug like this because you're just like nothing else is working so let's talk about what are do we still have continue it's a year later since we did a last show do we have has our mind changed on anything do we have still continuing concerns because this is a thing this is the same thing you referred to it just in passing as a cheat drug I don't actually think of this I don't think the idea of these drugs is cheating I really don't know I know there's people that disagree with me I know that I like I and I get the other side of it where it's like you need to work for what you earn you'll value it more it's the lessons in the journey and you know and you know it's not good to get on a drug like this

41:11and then not exercise or care about what you eat you're just you're just killing your hunger true I understand that but I don't have a problem for especially for the people like the guardian type people that we just talked about they have it really hard and sometimes just genetically people have it really hard if there really was a magic pill that did not have a downside like a legit major downside or risk or whatever you want to call it I don't I'm for it like I want people to be healthy like I don't really care I don't really care you guys can disagree or agree I don't get you but I don't I don't my biggest concern or complaint with this class of drugs is not that I think it's cheating at all like I don't if it was really the magic bullet that everybody's been hoping for and that some people really would appreciate then I'd be fine with it but I really do still have two major concerns I have more than that but these are my two major ones and I and I voice these on Instagram quite a bit and I think I did mention it in our last show but I'm going to say it again my two biggest concerns are well my one biggest concern is that you really only have two options with these drugs you can be on

42:15them for a while lose a bunch of weight because you're not hungry and then get off of it and you guys when you do that you gain all the weight back I mean almost 100% of the time you gain it all back sometimes you gain back even more we've seen that I am in a network of other coaches and just word of mouth just talking to each other about what we're seeing I've seen people gain back twice as much three times as much down the road after they've gotten off it you know the Boston medical journal you guys in this perfect timing for the show just put out a it's not just study it's a meta analysis sorry I said Boston sorry the British medical journal the BMJ just put out a meta analysis on basically well here is the title weight regained after cessation of medication for weight management so and really they're looking we're talking about the G.O.P. line drugs okay so just basically it analyzed is many valid studies as they could find and I

43:15think they ended up looking at 37 to see like okay what happens when people get off of the drug right not because everybody loses I mean if you're taking a big enough dose you'll lose weight when you're on it you're not eating at least in the short term you'll lose weight and it I mean you guys like every like they're can already do the conclusion this review found the cessation of these weight loss drugs is followed by rapid weight regain and reversal of beneficial effects on cardiometabolic markers so not only do you gain all the weight back it takes time you know anywhere from a year to a year and a half they say you're usually back at what we would call your original set point where you were before but also all of the good you know the facet insulin the glucose levels like all of the all of those things those go away too all of so like I said at start they only work when you're on them these findings suggest caution in short term use of these drugs without a more comprehensive approach long term use is better well but that's that's what that's the dilemma that's the Sophie's choice here so that's back to what I was saying my

44:19biggest concern is that either you're on it for a while and you get off of it thank you British Medical Journal for confirming what we already knew and I've been saying this for the start you're going to gain it all back and this is the thing and then I'll get to the second option yeah you go back to your original set point but my argument would be you would be back there but even worse because you're going to have a lower metabolic rate due to how long you would been under eating you're going to have less muscle you're going to and who knows if you're still going to have functioning naturally producing GLP and GIP we don't really know like if you're on an agonist like this where you're barraging your receptors for you know three years or how long you're on it I don't even know like how disruptive that is to leptin, grellin these are other hungering satiety hormones I don't know if your natural GLP GIP production comes back online I mean I have so many questions but I'm just going to say that you're going to end up on the other side if you come off of this overall in a worse spot that not just weight gained back but in a worse spot with a lower metabolic rate possibly hungry

45:23or all the time then when you started so like that's terrible okay and the only other option is to do what this is inferring and what the black box of these drugs says and that's to stay on them forever okay so I mean and like we already said to my knowledge the longest study we have is seven years which is not even close to the multi-generational design that these drugs have and I want to note this according to Dr. Zachary Knight I've followed him a decent amount on this he's a PhD out of University of California he's very well educated on these drugs he's actually quite pro them he's for them but according to him the these agonists work on the receptors for GLP and GIP at a thousand to ten thousand fold those hormones normal effects okay so we are ranking on these okay this is not the same as regular bio identical hormone replacement

46:24where maybe you're like okay well you used to have a testosterone of 75 and that's where you feel good now it's a 17 so we're going to add some back in to bring you back to where you naturally work where you feel good you can benefit you know all the protective things of this hormone that makes sense now if we win in with that same testosterone and gave me a thousand to ten thousand fold wouldn't people be concerned like I have never heard of a hormone being mimicked or amplified to this level without people really being concerned about it so I have all kinds of concerns in terms of trying to do that forever number one will will we see receptor blowout will they just stop will they just stop working because that is that is huge what we're doing it is not a physiologic this is super super physiologic amount of hormone mimicking that we're doing so that that's a concern and I mean who wants to be on a drug for the rest of their life honestly I just I think that's I think that's a valid question in and of itself and I'm very very very skeptical that these drugs are going to continue to work

47:25the same way that they're working now for example if you're like a near two in 20 years I really am very skeptical about that and we have no way of knowing so really those are my biggest concerns they've been my biggest concerns from the start and I've just not heard a good answer for either you have to get off it you're going to wait all gain it all back and be in a worse spot or you have to stay on it forever and that's a risk I would I would not want to take unless I was like I don't know really really desperate and really in a pickle because I just don't see this ending well we're already seeing like you're already seeing people say things like and I hear it all the time I'm on the highest dose of Terzepetide so now what do I do so you tight trade up and then you see you know you start low you get some results and then you're you plateau and then you tight trade up and then you get some results and then you plateau and then you tighten so it's just like okay we're already seeing that the body is adaptive that's normally how it is you're keep how you keep having to crank your dose up in order to see any change so I just don't see how you get

48:27at that max dose how long that's going to work you know what I'm saying like that's a huge concern and I just don't think people are thinking this through like I don't think they're just like give me thin now give it to me now you know so those are my two biggest concerns those have been my concerns from the start I still carry them I have not I have not no one's answer them no one's changed my mind on that we are already starting to see people come off of it for whatever reason to be expensive they don't want to be a drug the rest of life the side effects are too much you know whatever the reason is the weight regain is pretty much cataclysmic it's it's pretty intense it is pretty severe we're also starting to see now lots of experts very quietly walking back their enthusiasm for it just like we've seen with the fasting movement they're quiet about it you know because it's a little embarrassing but it's just like quietly putting out doctor Amy Horniman mine pump just did a just it up episode on like things you might want to watch out for maybe the kinds of people who shouldn't be on GLP one there's a ton of concern with them just being abused

49:28obviously the dose being too high you know weight loss being taken too far people who shouldn't be on it being on it and bone loss bone loss is a legit concern it's arguing issue for women who aren't on the drug so you add in you know here only 800 calories a day bone loss is a huge concern I think we're gonna see huge fallout in the next five to 10 years just in the osteophenia osteoporosis realm I mean that's just one of many concerns on the health side of things so we're just starting to hear people walk it back because these are very very powerful drugs so let's end with unless you have something else to say let's end with who who do we think they are for I mean you know what I mean and I this is what I said this is what I try to say on this show is number one I don't think we should take a drug ever that nutrition and lifestyle adjustments could fix and I think you know we kind of talk through a lot of the different categories of people who are maybe thinking no this is my only option this is what I need to do I think a lot of you

50:28if you have the right information the right doctor the right coach whatever you probably could get your health to where you wanted it if you're really willing to make the changes get your hormones figured out de-stress your life sleep more reverse diet all those things they're not easy but better than a drug so I would that would that would take care most of the population if they're if they're don't do not be taking a drug if lifestyle nutrition exercise whatever combination you need to do could could fix those problems okay beyond that if you're one of those people who just genetically hit what is the opposite of a jackpot hit the diabetes jackpot we'll say that and there aren't a ton of you but you are out there where it's like mom and dad gave this to you you came out insulin resistant and like you look at a brownie and you gain weight like you know you're out there okay maybe it's somebody who's dieted so hardcore for so long that you are just metabolically in such a bad spot you know I don't know I'm just trying to think of extreme cases where maybe you would it would might be reasonable to weigh the pros and the cons and there are a lot of cons

51:32so you always need to be weighing that when you're talking about any kind of drug intervention if you need to be on something or maybe you're just so diabetic that like the the diabetes is going to kill you dead and so you're just weighing like okay there are a lot of negatives but I also don't want to die this disease so I'm weighing it and I think that the drug is worth it right now okay I mean that's the kind of people this was designed for I would say go for the lowest dose possible absolutely the lowest dose possible I would try to work with a provider who knows what they're doing and will help you cycle on and cycle off so as to maintain receptor sensitivity okay I really think that's important you see that in the peptide world that's what everyone does with all the other peptides so they don't blow out the receptors okay so lowest dose possible cycle on cycle off make sure you're making all the lifestyle changes exercise nutrition all the things that you possibly can before that and during that okay and one thing I'm going to note for you guys who think you're micro dosing dosing is a huge issue right now micro dosing is like then you know it's like the newest trend but I don't think anybody knows what micro dosing is like so many of you are getting sold a GLP and they're like yeah it's a micro dose but really it's a starting dose so do your research and make sure that that's what's going on and I'll just tell you this right now if you start your micro dose and you drop 20 pounds

52:55in two or three weeks that's not a micro dose okay a micro dose is anywhere from a fifth to a tenth on average maybe even less of a starting dose many of you who think you're on a micro dose are not okay and ultimately if you're going to play around with these drugs even at a low dose you have to have and you need to have an exit strategy you need to think through what do I do when I get off of it for all the reasons that we just talked about British medical journalism it's not good for you guys so I would utilize these drugs I would consider them as an absolute lash before. Very good baby. Yeah. Well make sure you check out our last show on a Zimbeck on that a year ago. A year ago I'll try to include that in our show notes and everything but make sure you also share our show and share with other friends. No. This is hopefully a good conversation, helpful conversation and a conversation that probably most people aren't having at some level so share the show around. Appreciate you guys supporting.

53:55We will be in the studio likely next week. I love another show going on. I think pretty much for September. We just got to record on it every day. Oh yeah let's try it. Alright thank you guys for joining water break and we'll see you next week. Bye guys.