Psychedelics for Treating Mental Disorders | Dr. Matthew Johnson

This episode I discuss medical research on psychedelic compounds with Dr. Matthew Johnson, Ph.D., Professor of Psychiatry and Behavioral Sciences at Johns Hopkins School of Medicine. We discuss the biology and medical clinical-trial uses of psilocybin, MDMA, ayahuasca, DMT, and LSD. Dr. Johnson teaches us what the clinical trials in his lab are revealing about the potential these compounds hold for the treatment of depression, addiction, trauma, eating disorders, ADHD, and other disorders of the mind. Dr. Johnson describes a typical psychedelic experiment in his laboratory, start to finish, including the conditions for optimal clinical outcomes. And he explains some of the potential hazards and common misconceptions and pitfalls related to psychedelic medicine. Dr. Johnson explains flashbacks, the heightened risks of certain people and age groups using psychedelics and the ever evolving legal and pharmaceutical industry landscape surrounding psychedelics. Dr. Johnson also explains how the scientific study of psychedelics is likely to set the trajectory of psychiatric medicine in the years to come. Dr. Johnson is among a small handful of researchers who have pioneered the clinical study of these powerful compounds. He has unprecedented insight into how they can be woven into other psychiatric treatments, changing ones sense of self and of reality. Read the full show notes for this episode at hubermanlab.com. Thank you to our sponsors AG1: https://athleticgreens.com/huberman LMNT: https://drinklmnt.com/hubermanlab Waking Up: https://wakingup.com/huberman Momentous: https://livemomentous.com/huberman Timestamps 00:00:00 Introducing Dr. Matthew Johnson   00:02:27 Sponsors: AG1, LMNT & Waking Up 00:06:40 ‘Psychedelics’ Defined   00:14:09 Hallucinations, Synesthesia, Altered Space-Time Perception   00:19:56 Serotonin & Dopamine   00:23:50 Ketamine & Glutamate   00:28:00 An Example Psychedelic Experiment   00:37:30 ‘Letting Go’ with Psychedelics   00:44:10 Our Mind’s Eye   00:48:00 Redefining Your Sense of Self   00:58:56 Exporting Psychedelic Learnings to Daily Life   01:04:36 Flashbacks   01:12:10 Ayahuasca, ASMR, Kundalini Breathing   01:15:54 MDMA, DMT   01:26:00 Dangers of Psychedelics, Bad Trips, Long-Lasting Psychosis   01:38:15 Micro-Dosing   01:56:45 Risks for Kids, Adolescents & Teenagers; Future Clinical Trials   02:03:40 Legal Status: Decriminalization vs. Legalization vs. Regulation   02:18:35 Psychedelics for Treating Concussion & Traumatic Brain Injury   02:27:45 Shifting Trends in Psychedelic Research, Academic Culture   02:44:23 Participating in a Clinical Trial, Online Survey Studies, Breathwork   02:50:38 Conclusions, Subscribing & Supporting the HLP, Supplements   Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices