TFP #007 - Nicholas Verhoeven PhD: Deep Dive on LDL, Causation & Scientific Method

In this episode of The Feldman Protocol, Dave Feldman sits down with Nicholas Verhoeven PhD, the creator of @Physionic and recent molecular medicine graduate who has successfully transitioned from traditional academia to independent science communication. The conversation explores Nic's unique approach to content creation, including his decision to reject thousands of sponsorship offers to maintain editorial independence while building a sustainable business model. Dave and Nic dive deep into the methodology and findings of Dave's groundbreaking longitudinal keto study, examining how 100 lean mass hyperresponders with an average LDL of 272 mg/dL compared to matched controls from the Miami Heart study with an average LDL of 123 mg/dL. The discussion reveals fascinating insights about plaque progression, the challenges of proving causation in nutrition science, and the problematic certainty often displayed in epidemiological research. They tackle the nuanced differences between correlation and causation, critique the WHO's red meat classification, and explore why the nutrition field tends toward binary thinking rather than acknowledging the spectrum of evidence strength that should inform our understanding of health risks.

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