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Is your NAD+ supplement actually working against you?
Millions of people are taking NMN or NR thinking they're
doing something smart for their longevity. And the science
behind NAD+ is genuinely extraordinary. But the way most
people are supplementing it is incomplete — and there's
growing evidence it could be creating downstream harm most
people never connect back to their supplement.
In this episode I break down the full NAD+ story — the
methylation trap, the CD38 drain, why high-dose NMN may be
elevating your cardiovascular risk markers, and what an
intelligent systems-level approach actually looks like.
I co-developed NAD+ Next Gen with Peter Lehrke— and in this episode I walk
you through exactly why every ingredient is in the formula.
WHAT WE COVER:
- The 2023 Nature Cardiovascular Research findings on NMN & ADMA
- How high-dose NMN drains your SAM pool and disrupts dopamine,
DNA methylation and homocysteine
- CD38 — the biggest NAD+ drain in ageing nobody talks about
- The bathtub model: precursors, drains, sirtuin efficiency
- Why niacinamide may be smarter than high-dose NMN
- EGCG, resveratrol, apigenin, quercetin, rutin — the why
behind each ingredient
- 6 practical takeaways including which blood test to get now
KEY LINKS:
NAD+ Next Gen → https://aevumlabs.co.nz
Rejuvenate Pro → https://shop.lisatamati.com
Pushing The Limits community → https://www.lisatamati.com
GET YOUR HOMOCYSTEINE TESTED:
Optimal: below 7–8 µmol/L
Above 10 µmol/L: address your methylation cycle urgently
Lisa Tamati is a functional health practitioner, longevity
specialist, co-founder of Aevum Labs, host of Pushing The
Limits, and former elite ultra-endurance athlete with 25
years and 140+ ultramarathons across the world's most
extreme environments.
Visit Lisa's website
shop.lisatamati.com
www.Yourhealthcompass.org
www.Myimmuneage.life
No transcript available for this episode.