The Dark Side of NMN Nobody Tells You About

Is your NAD+ supplement actually working against you?

Millions of people are taking NMN or NR thinking they're 
doing something smart for their longevity. And the science 
behind NAD+ is genuinely extraordinary. But the way most 
people are supplementing it is incomplete — and there's 
growing evidence it could be creating downstream harm most 
people never connect back to their supplement.

In this episode I break down the full NAD+ story — the 
methylation trap, the CD38 drain, why high-dose NMN may be 
elevating your cardiovascular risk markers, and what an 
intelligent systems-level approach actually looks like.

I co-developed NAD+ Next Gen with Peter Lehrke— and in this episode I walk 
you through exactly why every ingredient is in the formula.

WHAT WE COVER:
- The 2023 Nature Cardiovascular Research findings on NMN & ADMA
- How high-dose NMN drains your SAM pool and disrupts dopamine, 
  DNA methylation and homocysteine
- CD38 — the biggest NAD+ drain in ageing nobody talks about
- The bathtub model: precursors, drains, sirtuin efficiency
- Why niacinamide may be smarter than high-dose NMN
- EGCG, resveratrol, apigenin, quercetin, rutin — the why 
  behind each ingredient
- 6 practical takeaways including which blood test to get now

KEY LINKS:
NAD+ Next Gen → https://aevumlabs.co.nz
Rejuvenate Pro → https://shop.lisatamati.com
Pushing The Limits community → https://www.lisatamati.com

GET YOUR HOMOCYSTEINE TESTED:
Optimal: below 7–8 µmol/L
Above 10 µmol/L: address your methylation cycle urgently

Lisa Tamati is a functional health practitioner, longevity 
specialist, co-founder of Aevum Labs, host of Pushing The 
Limits, and former elite ultra-endurance athlete with 25 
years and 140+ ultramarathons across the world's most 
extreme environments.

Visit Lisa's website 

www.lisatamati.com

shop.lisatamati.com

www.longlifehyperbarics.com

www.aevumlabs.co.nz 

www.Yourhealthcompass.org

www.Myimmuneage.life 

Work with Lisa: