The FIRST Sign of a Vitamin A Deficiency Is...

R.E.I. co-op knows when you're up at 4.30 a.m. on a Saturday for a long run and you're

actually excited.

Not everyone gets it, but we do.

At R.E.I., we're here for people who get outside.

Share up for your next run in store or at R.E.I. dot com.

Zootopia 2 has come home to Disney Plus.

Let's go!

Get ready for a new case.

We're the greatest partners of all time.

New friends.

Go eat the snake.

And your last name?

The snake.

Dream team.

New habitats.

Zootopia has a secret reptile population.

You can watch the record breaking phenomenon at home.

Zootopia 2.

Now available on Disney Plus rated PG.

Here right now you can get Disney Plus and Hulu for just $4.99 a month for three months with

a special limit to time offer ends March 24th.

After three months playing auto renews at $12.99 a month, terms apply.

What do you think the first sign of a vitamin A deficiency would manifest as in your body?

Now if you guessed Nictalopia, you are correct.

Now what is this Nictalopia?

I mean it's kind of funny sometimes when people give you these words that you might not understand.

Then you tell them like, what does that mean?

They might slow it down like Nictalopia.

I'm like, that doesn't help me.

I need to know what that means.

So you have to get a dictionary out and look up the word.

But Nictalopia basically is night blindness.

Okay, you can't see in the dark too well.

So whether you're driving home in the dark and you're having a hard time seeing the road.

Or it's raining out and it's dark and you really can't see the road.

Or even if you're in your house, your office reading a book.

And there's not good lighting.

Okay, you may think you need glasses.

When in fact, you might need vitamin A.

Now I will say that if you spend any amount of time reading your phone, looking at your computer screen.

Like I do many, many hours a day.

What's going to happen is the muscles on the eye go into a spasm.

Okay, and they stay in this little spasm.

Which then will affect your ability to see.

And you go to the eye doctor and you'll be fitted for something like this.

Which is interesting because when I went there, I asked the ophthalmologist.

I said, why do we need glasses?

Is it a genetic problem?

And he goes, yeah, it's a genetic problem.

I said, that doesn't make sense to me.

And then I asked him, I said, looking at a computer screen or reading a book for long periods of time.

Doesn't that affect the vision?

He says, well, I can't disagree with you.

That probably does.

But honestly, these eye doctors probably are not taught a lot of preventative type things to prevent you from developing this spasm in your eye.

What I would highly recommend, and I put this in a video, is to get outside every single day to try to counter this spasm going on the eye by looking in the distance, looking at trees, looking at things and focusing in on purpose, various things in your environment.

For at least an hour a day, that would be very therapeutic.

And the chances of you needing glasses would be greatly lessened.

In fact, if you have glasses, you'll probably improve your eyes over time if you did that.

But if you have difficulty seeing in dim lighting or at night while you're driving, suspect a vitamin A deficiency.

Now, there's some interesting things about vitamin A.

The active form of vitamin A is called retinol.

So why did they come up this name retinol for vitamin A?

Could it be that it has something to do with the retinol, which is the back part of the eye?

It's an extension of your brain that allows you to see.

So vitamin A retinol, the active form, not beta-carotene, which is the precursor that has to convert into retinol.

Retinol is needed to help you create this little protein in your eye that converts light to electrical signals.

And that's called visual purple or redopsin.

So vitamin A is needed to form this pigment for these little things in your eyes that are called rods.

And these little rods help you see in the peripheral area of your vision, as well as low illuminated areas.

That's right. Now, I want to touch on this precursor beta-carotene that converts into retinol.

It amazes me that they actually, I think they changed the definition, I don't know how long ago, that beta-carotene, the precursor, is vitamin A.

Well, it's not the active form of vitamin A. It's the precursor.

And it has to be converted into retinol.

Let's just kind of compare the amount of retinol that's in three ounces of beef liver because beef liver is very, very high in retinol.

Okay, three ounces.

How much beta-carotene in carrots would you need to have the same retinol?

Okay, as in three ounces of beef liver, you would need 40 pounds of raw carrots.

That would be very difficult to consume. I mean, I can see like 20 pounds, but 40 pounds of carrots, it's not going to happen.

All right, how much kale would you need to equal the amount of retinol and just three ounces of beef liver?

Well, you need 454 cups of raw kale to equal the retinol and only three ounces of beef liver.

Incredible. It's probably not going to happen.

So if you're doing three or four or five cups of kale in your salad, whatever, and you think you're getting enough true vitamin A, chances are you're not.

What type of foods are high in vitamin A, of course?

Exama is unpredictable, but you can flare less with eggless, a once-monthly treatment for moderate to superior eczema.

After an initial four-month or longer dosing phase, about four and ten people taking eggless, achieved itch relief and glare are almost glare skin at 16 weeks.

And most of those people maintain skin that's still more glare at one year with monthly dosing.

Hempless, LibriKizumap, LBKZ, a 250 milligram per 2 milliliter injection is a prescription medicine used to treat adults and children 12 years of age and older who weigh at least 88 pounds or 40 kilograms with moderate to severe eczema.

Also called a topic dermatitis that is not well controlled with prescription therapies used on the skin or topicals or who cannot use topical therapies.

Eczema can be used with or without topical corticosteroids.

Don't use if you're allergic to eczema, allergic reactions can occur that can be severe.

Eye problems can occur, tell your doctor if you have new or worsening eye problems.

You should not receive a live vaccine when treated with eczema before starting eczema, tell your doctor if you have a parasitic infection.

Ask a doctor about eczema and visit eczema.com or call 1-800-LilyRX or 1-800-545-5979.

This episode is brought to you by Athletic Brewing Company, no matter how you do game day.

On the couch, in the crowd, or manning the snack table, Athletic Brewing fits right in.

With a full lineup of non-alcoholic beer styles, you can enjoy bold flavors all game long.

No hangovers, no buzz, no subbing out for water in the second half.

Stuck the fridge for tip-off with a variety of non-alcoholic craft styles available at your local grocery store or online at AthleticBrewing.com.

Near beer, fit for all times.

Grass-fed beef liver, egg yolks, cod liver oil.

Now, fish oil has omega-3 fatty acids, but not the vitamin A, like cod liver.

Cod liver oil has omega-3 fatty acids, as well as vitamin D and vitamin A.

Raw cheese has a good amount of vitamin A, raw cream and raw butter has a good amount of retinol.

But, pasteurization destroys vitamin A.

So, if you're getting pasteurized milk or pasteurized cheese, which is the majority of cheese or pasteurized butter,

or even if you're eating a lot of overly cooked carrots or cooked vegetables that has the precursor,

you're not going to get a lot of vitamin A.

Now, if you're doing cheese, try to get raw milk cheese.

If you can get sheep cheese, you'll get a lot more vitamin A.

In fact, there's another animal milk that you can get to get a good amount of vitamin A,

and that is actually rat milk.

So, if you run out of sheep cheese milk, you always have a plan B.

So, vitamin A is needed to prevent night blindness, to be able to see in the dark somewhat.

It's also needed to prevent dry eyes.

It's also needed to help the eye compensate.

So, this is probably why if someone's very, very deficient in vitamin A,

they're going to have a hard time focusing in on different things,

because another symptom of vitamin A deficiency is dry eyes, but also dry skin.

Vitamin A is also necessary for any type of skin differentiation.

So, if you don't have an vitamin A, your skin might not turn into a nice soft skin.

It might be rough, scaly, dry skin.

It's also needed to help the eye compensate for distances as well.

So, some of the accommodation reflex is dependent on a certain amount of vitamin A.

Vitamin A is desperately needed to prevent infections,

because it's very important for your immune system.

And I'm not just talking about the external skin.

I'm talking about also problems with the internal skin,

like the mucus membranes of your sonuses,

like the internal skin of the esophagus, of the stomach, of the intestines,

can all be affected by a vitamin A deficiency.

And as a child is developing early on,

that child needs a good amount of vitamin A.

So, this relates to why certain people are deficient, right?

A woman who's pregnant, right, is more susceptible to having a vitamin A deficiency,

because of the demand for vitamin A goes up.

Also, if she's breastfeeding, she needs more vitamin A.

This is probably why your grandmother, or your parents,

recommended a spoonful of cod liver oil on a regular basis.

Mm-hmm, delicious cod liver oil.

So, other reasons why people are deficient is having this false idea

that beta-carotene is retinal.

It's not.

Beta-carotene has to be converted into retinal to be active.

And that leads to another reason why a person might be deficient in vitamin A.

Well, there's something called polymorphism.

That is the genetic mutation that can affect certain things in your body.

But apparently, the gene that converts beta-carotene into retinal

could be a polymorphic gene.

It could be mutated.

In fact, there's a study I read that shows that it's pretty common to have a problem

with that gene that converts beta-carotene into retinal.

So, that could be another reason why someone is deficient in retinal,

because they might be consuming a lot of beta-carotene.

It's not converting, or they might be consuming in the active form of vitamin A,

yet they have this genetic weakness.

And by the way, if that's the problem, I would recommend not just increasing

the amount of retinal foods.

Okay.

I would also add bile salts.

And maybe another type of bile salt called tutka to increase more absorption.

And of course, that's the perfect segue to another reason why people are deficient

by the vitamin A.

They don't have enough bile.

They have bile problems.

Let's say they have gallstones, or they had gallstones, or they had the gallbladder removed,

or they have sludge in the gallbladder, or they have a fatty liver,

or some of the problem with the liver, that makes bile.

There's a lot of reasons why you might not have enough bile.

It also could be you took an antibiotic.

The microbes in your gut actually make a certain type of bile as well.

So that could be another reason.

Let's say, for example, you are in a low-fat diet.

Of course, if you're in a low-fat diet, you're not going to be eating the foods high in retinal.

Let's see you're in a medication called statin that blocks your ability to turn cholesterol into bile.

You end up with a bile deficiency.

So taking statins can actually give you a vitamin A deficiency.

This is Andrew Huberman, host of the Huberman Lab podcast.

I'm excited to share that the performance eyewear company Roca and I have teamed up to create a pair of red lens glasses.

These are meant to be worn in the evening after the sun goes down.

They filter out short wavelength light that comes from screens and from LED lights,

which are the two most common indoor lights nowadays.

I want to emphasize that these are not traditional blue blockers.

Yes, they filter out blue light, but they also filter out all the other wavelengths of light

that can suppress your melatonin and other hormones, which can degrade your sleep.

By wearing these glasses in the evening, I find it much easier to wind down at night

and it makes the transition into sleep greatly improved.

If you would like to try these red lens wind-down glasses, simply go to roca.com.

That's roca.com and enter the code Huberman to save 20% off your first order.

Again, that's roca.com and enter the code Huberman at checkout.

Spring is here and the shopping list is long.

Time to make a lows run.

Buy three bags, get three free.

Stay green, one cubic foot garden soil.

Plus, right now, members can earn four times the points on an eligible purchase.

Start spring off strong with these deals and more.

Our best lineup is here at Loves.

Valent the 325, while supplies last.

Soil offer excludes a lasken Hawaii.

Lowell T-Program subject to terms and conditions.

Sealows.com slash terms for details.

Subject to change. Point booster, subject to exclusions and more terms apply.

One time I'll only offer.

And the last point on why you might be deficient is just some knowledge on vitamin A gets destroyed with heat.

So if milk is pasteurized, if someone consumes milk and it's not raw and just pasteurized,

they're not going to get a vitamin A.

Or let's say they're consuming a lot of carrots or kale that's overly cooked.

Okay, well, that just destroys the precursor.

So it's not going to turn into retinal.

Or again, you're not consuming raw cheese.

You're just doing the regular pasteurized cheese.

Another problem.

Alright, so now you definitely know more about vitamin A.

Okay, I think the next best video for you to watch would be the one on cop different whale.

So check that out.

I put it up right here.

Tires matter.

They're the only part of your vehicle that touches the road.

Spread confidently with new tires from tire rack.

Whether you're looking for expert recommendations or know exactly what you want,

tire rack makes it easy.

Fast, free shipping, free road hazard protection, and convenient installation options.

Go to tire rack.com to see tire test results, tire ratings, and consumer reviews.

And be sure to check out all the special offers, tire rack.com, the way tire buying should be.

Rinse knows that greatness takes time, but so does laundry.

So rinse will take your laundry and hand deliver it to your door, expertly cleaned.

And you can take the time pursuing your passions.

Time one spent sorting and waiting, folding and queuing, now spent challenging and innovating,

and pushing your way to greatness.

So pick up the Irish flute or those calligraphy pens,

or that daunting beef Wellington recipe card, and leave the laundry to us.

Rinse, it's time to be great.