Isabel de Portugal
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Isabel de Portugal (1503-1539) was the Queen of Castile and León, wife of King Charles V of the Holy Roman Empire. She was the daughter of King John II of Portugal and was married to Charles V at the age of 16. She played an important role in the royal court and was known for her intelligence and strong will. She was also a patron of the arts and education. Isabel died at the age of 35 due to complications from a fev...
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