This Week in Startups
Jason Calacanis covers startups, tech, markets, media, and all the hottest topics in business and technology. He also interviews the world’s greatest founders, operators, investors, and innovators.
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Episodes (1471)
Dr. Mark Hyman on Function Health & GLP-1 microdosing | E2334
This Week in Startups
Becki DeGraw on spinouts, IP licensing & clean exits | Wilson Sonsini Startup Le...
This Week in Startups
VC experts on why Physical AI funding is heating up | E2333
This Week in Startups
Are AI Agents forming "civilizations" or is this just a psy op? | 2332
This Week in Startups
Breaking down Nvidia's Hugging Face and Poolside bets | E2331
This Week in Startups
Bill Gates foresees massive AI job loss: these VCs disagree | E2330
This Week in Startups
You Can't Fire a VC From Your Board: Here's Why | Wilson Sonsini Startup Legal B...
This Week in Startups
China wants you to cheer for the robots taking your job | E2329
This Week in Startups
Open source is going to win it all: Harvey proves it | E2328
This Week in Startups
Taste is the new programming language (w/ Astrocade CEO Amir Sadeghian) | AI Bas...
This Week in Startups
Neurosymbolic AI outperforms chatbots and product search | E2327
This Week in Startups
Bittensor creator Const on Affine, dTAO, "mining reasoning," and more | E2326
This Week in Startups
What we'll learn from Anthropic's $2-$3T IPO | E2325
This Week in Startups
These robots could cut delivery costs by 80% | Next Unicorns
This Week in Startups
Zuck's AI manifesto is a data center PR masterclass | E2323
This Week in Startups
How AI splits startups into winners and losers | E2322
This Week in Startups
Airtable's 80% off value crash: VCs explain why it's still a win | E2321
This Week in Startups
How Bespoke faked AI until it actually worked (w/ Akemi Tsunagawa) | E2320
This Week in Startups
Why AI has no taste and how to fix it (w/ Thais Castello Branco) | E2319
This Week in Startups
Banning Chinese robots isn't regulatory capture | E2318
This Week in Startups
While other cultivated meat companies are collapsing, this one turned a profit |...
This Week in Startups
Why quantum has been "10 years away" for 30 years | E2316
This Week in Startups
Why this longevity startup raised in Japan, not Silicon Valley | TWiST Tokyo | E...
This Week in Startups
The AI Securing Your Workforce Before a Mistake Ever Becomes a Breach | E2314
This Week in Startups
The dawn of surgery bots + buy a home for $250 (w/ Andromeda & Mogul) | E2313
This Week in Startups
A Startup Is Trying to Buy PayPal… Craziest Deal of 2026! | E2312
This Week in Startups
Jason turned $11 and one tweet into 1.1M views | E2311
This Week in Startups
Danny Bernstein left Big Tech to fund farm-bots | E2310
This Week in Startups
Why Data Is the Next $1 Trillion Market
This Week in Startups
$100T is managed by "human duct tape" | E2308
This Week in Startups
Why the VC Hype Cycle Always Gets It Wrong | VC Roundtable | E2307
This Week in Startups
Chamath on why young people need more agency, risk, and adventure
This Week in Startups
Why F1 Teams are Replacing Wind Tunnels with Smart Tape | E2305
This Week in Startups
Why the Future of Video Games is Moving Back to the Dinner Table
This Week in Startups
The hottest running app has nothing to do with speed | E2303
This Week in Startups
Why SpaceX Buying Cursor Changes Everything
This Week in Startups
The Startup Building the First Hotel on the Moon…
This Week in Startups
SpaceX IPO Day: What Wall St. and the media missed | E2300
This Week in Startups
Why the most expensive Seed deals are the cheapest | E2299
This Week in Startups
The AI Tutor That Makes Kids Actually Think | E2298
This Week in Startups
Anthropic wants to slow AI down and Bernie wants 50%: JCal Reacts | E2297
This Week in Startups
The project SpaceX's first employee raised $500M for
This Week in Startups
This Startup Fused Human Brain Cells with Silicon Chips | E2295
This Week in Startups
How to Raise a Seed Round in 2026: Ask Jason | E2294
This Week in Startups
The Drone Company Quietly Taking Over Delivery
This Week in Startups
From hypercars to cruise missiles: Lukas Czinger on the future of US defense | E...
This Week in Startups
Avi Patel on the startup that copied Kled and why he called out General Catalyst...
This Week in Startups
Why does Gen Z hate AI?
This Week in Startups
The Self-Driving Startup Nobody Saw Coming | E2289
This Week in Startups
How Many Startups Will Survive OpenAI? | E2288
This Week in Startups