#406: Peptide OVERLOAD: When Biohacking Backfires (How NOT to Crash Your Mitochondria) With Anthony Castore

Today, I'm joined by the incredible Anthony Castore, a trailblazer who fuses elite strength coaching with deep cellular medicine. In our conversation, Anthony shares his journey from a young athlete determined to defy genetic odds to becoming an expert in both physical training and the nuanced science of peptides, mitochondria, and bioregulators.

 

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Episode Timestamps:

Welcome and episode introduction ... 00:00:00

Anthony Castore's path from strength coaching to cellular medicine ... 00:05:55

Connecting strength training with cellular pathways (AMPK, mTOR) ... 00:12:27

Explaining and balancing AMPK and mTOR for performance ... 00:13:03

Training strategies: Metabolic, hypertrophy, and neural approaches ... 00:18:18

Building a solid foundation: Lifestyle, training, nutrition, peptides ... 00:23:04

Assessing recovery capacity and individualizing protocols ... 00:26:02

Mitochondrial fission, fusion, and targeted adaptation ... 00:29:57

Optimizing muscle gain and fat loss through calories and recovery ... 00:31:00

Differentiating bodybuilder vs. longevity approaches ... 00:34:44

Integrating peptides and support molecules into routines ... 00:40:44

Ketone esters and mitochondrial peptide interventions ... 00:41:20

Cautions on stacking and combining interventions ... 00:54:04

Lessons learned from overdoing interventions ... 01:05:02

 

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