Artificial Intelligence, Urolithin-A & Cold Water

Iron Radio: AI’s Impact on Coaching & Peer Review, Urolithin A in Sports Nutrition, and Cold Water Immersion Updates

On Iron Radio, hosts Dr. Lonnie Lowery and Dr. Mike T. Nelson discuss how AI may speed content distribution, assist with business tasks, and potentially replace some lower-level coaches while still lacking context for peer review and research interpretation, raising concerns about regulation, healthcare profit motives, and data-center resource demands. They revisit urolithin A (a gut microbiota–derived metabolite linked to mitochondrial effects), referencing a 2025 Frontiers in Nutrition paper and Mike’s personal and client experiences, noting modest perceived recovery/HRV benefits, high cost, and possible responder differences due to gut conversion. Mike also summarizes a broad review on cold exposure and metabolism across organ systems, highlighting mixed recovery data, evidence that immediate post-hypertrophy cold-water immersion can reduce muscle protein synthesis via reduced blood flow, lack of clear anti-inflammatory marker changes, and practical guidance based on season, logistics, and athlete preference.

00:00 Welcome to Iron Radio

01:13 Mike’s Vegas Mastermind

01:30 AI for Content Creation

03:18 AI Limits and Assumptions

03:57 Peer Review and Academia

05:42 Jobs at Risk in Healthcare

10:23 AI in Coaching and Diets

13:10 Regulation and Data Centers

15:24 AGI Race and Safety

17:36 Urolithin A Research Overview

20:49 Mike’s Experience with UA

22:33 Gut Conversion Variability

22:58 Iron Radio Feed Update

24:10 Free Daily Newsletter

24:48 New Supplements Book

25:57 Postbiotics and Skepticism

28:04 Safety First Testing

29:00 Cold Exposure Review

31:06 Hypertrophy Tradeoffs

35:31 In Season Ice Baths

40:03 Measuring Recovery Reality

43:15 Whole Body Effects

45:51 Wrap Up and Disclaimer

Donate to the show via PayPal HERE.

You can also join Dr Mike's Insider Newsletter for more info on how to add muscle, improve your performance and body comp - all without destroying your health, go to www.ironradiodrmike.com 

Thank you!

Phil, Jerrell, Mike T, and Lonnie