Episode 111: My Plant Medicine Experience w Ayahuasca and Kambo in Costa Rica

• Introduction to Marcos and his journey
• What to consider
• Lessons learned
• How my journey began
• Where I went
• What I took
• How I felt
• My takeaway
• Warnings

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Marcos https://www.linkedin.com/in/strongerfitness

Mike Bledsoe on IG https://www.instagram.com/mike_bledsoe/?hl=en

An Urgent Plea to Users of Psychedelics: Let’s Consider a More Ethical Menu of Plants and Compounds by Tim Ferriss

https://tim.blog/2021/02/21/urgent-plea-users-of-psychedelics-ethical-plants-compounds/

Amazon Conservation Team via Dr Mark Plotkin

https://www.amazonteam.org/

Kambo Casita, Nosoro Costa Rica  https://www.kambocasita.com/

Multidisciplinary Association for Psychedelic Studies (MAPS) is a 501(c)(3) non-profit research and educational organization that develops medical, legal, and cultural contexts for people to benefit from the careful uses of psychedelics and marijuana.

https://maps.org/

Dr Rick Doblin of MAPS podcasts

Rick Doblin: Psychedelics | Lex Fridman Podcast #202

Joe Rogan Experience: Dr Rick Doblin

https://open.spotify.com/episode/1Z8lzhvHCMv0c8qZWXbzzK

Mitchell, J.M., Bogenschutz, M., Lilienstein, A. et al.MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study. Nat Med27, 1025–1033 (2021). https://doi.org/10.1038/s41591-021-01336-3

Selected References

Ayahuasca(1-9)

Kambo (10-18)

1.         Dos Santos RG, Valle M, Bouso JC, Nomdedéu JF, Rodríguez-Espinosa J, McIlhenny EH, et al. Autonomic, neuroendocrine, and immunological effects of ayahuasca: a comparative study with d-amphetamine. Journal of clinical psychopharmacology. 2011;31(6):717-26.

2.         Hamill J, Hallak J, Dursun SM, Baker G. Ayahuasca: Psychological and Physiologic Effects, Pharmacology and Potential Uses in Addiction and Mental Illness. Curr Neuropharmacol. 2019;17(2):108-28.

3.         Estrella-Parra EA, Almanza-Pérez JC, Alarcón-Aguilar FJ. Ayahuasca: Uses, Phytochemical and Biological Activities. Nat Prod Bioprospect. 2019;9(4):251-65.

4.         Orsolini L, Chiappini S, Papanti D, Latini R, Volpe U, Fornaro M, et al. How does ayahuasca work from a psychiatric perspective? Pros and cons of the entheogenic therapy. Hum Psychopharmacol. 2020;35(3):e2728.

5.         dos Santos RG. Immunological effects of ayahuasca in humans. J Psychoactive Drugs. 2014;46(5):383-8.

6.         Zeifman RJ, Palhano-Fontes F, Hallak J, Arcoverde E, Maia-Oliveira JP, Araujo DB. The Impact of Ayahuasca on Suicidality: Results From a Randomized Controlled Trial. Front Pharmacol. 2019;10:1325.

7.         Dos Santos RG, Grasa E, Valle M, Ballester MR, Bouso JC, Nomdedéu JF, et al. Pharmacology of ayahuasca administered in two repeated doses. Psychopharmacology. 2012;219(4):1039-53.

8.         Winkelman M. Psychedelics as medicines for substance abuse rehabilitation: evaluating treatments with LSD, Peyote, Ibogaine and Ayahuasca. Curr Drug Abuse Rev. 2014;7(2):101-16.

9.         Palhano-Fontes F, Barreto D, Onias H, Andrade KC, Novaes MM, Pessoa JA, et al. Rapid antidepressant effects of the psychedelic ayahuasca in treatment-resistant depression: a randomized placebo-controlled trial. Psychol Med. 2019;49(4):655-63.

10.      Schmidt TT, Reiche S, Hage CLC, Bermpohl F, Majic T. Acute and subacute psychoactive effects of Kambo, the secretion of the Amazonian Giant Maki Frog (Phyllomedusa bicolor): retrospective reports. Sci Rep. 2020;10(1):21544.

11.      Roy R, Baranwal A, Espiridion ED. Can Overuse of Kambo Cause Psychosis? Cureus. 2018;10(6):e2770.

12.      Majic T, Sauter M, Bermpohl F, Schmidt TT. Connected to the spirit of the frog: An Internet-based survey on Kambo, the secretion of the Amazonian Giant Maki Frog (Phyllomedusa bicolor): Motivations for use, settings and subjective experiences. J Psychopharmacol. 2021;35(4):421-36.

13.      Rali P, O'Corragain O, Oresanya L, Yu D, Sheriff O, Weiss R, et al. Incidence of venous thromboembolism in coronavirus disease 2019: An experience from a single large academic center. J Vasc Surg Venous Lymphat Disord. 2021;9(3):585-91 e2.

14.      Byard RW. Is voluntary envenomation from the kambo ritual therapeutic or toxic? Forensic Sci Med Pathol. 2020;16(2):205-6.

15.      Peleg Hasson S, Shachar E, Kessner R, Shpigel S, Wolf I. Kambo-Induced Systemic Inflammatory Response: A Case Report of Acute Disease Progression of Cholangiocarcinoma. Integr Cancer Ther. 2021;20:1534735421999106.

16.      Junior VH, Martins IA. KAMBO: an Amazonian enigma. J Venom Res. 2020;10:13-7.

17.      Silva F, Monteiro WM, Bernarde PS. "Kambo" frog (Phyllomedusa bicolor): use in folk medicine and potential health risks. Rev Soc Bras Med Trop. 2019;52:e20180467.

18.      den Brave PS, Bruins E, Bronkhorst MW. Phyllomedusa bicolor skin secretion and the Kambo ritual. J Venom Anim Toxins Incl Trop Dis. 2014;20:40.