Episode 123: Keep Muscle During Fat Loss, Increase Performance, And Add Mitochondria: Lactate As a New Sports Supplement

• Lactate's  potential  benefits
• Lactate as a fuel source
• Why lactate gets a bad rap
• Review of a new study published in Current Research Physiology, September 2021: The Effect of Lactate Administration on Mouse Skeletal Muscle Under Caloric Restriction
  • Methodology
  • Testing
  • Results
• My thoughts on the  study
• Where more data is needed

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Selected References

Morris, D. (2012). Effects of oral lactate consumption on metabolism and exercise performance. Curr Sports Med Rep, 11(4), 185-188. doi:10.1249/JSR.0b013e31825da992. https://pubmed.ncbi.nlm.nih.gov/22777328/

Morris, D. M., Shafer, R. S., Fairbrother, K. R., & Woodall, M. W. (2011). Effects of lactate consumption on blood bicarbonate levels and performance during high-intensity exercise. Int J Sport Nutr Exerc Metab, 21(4), 311-317. doi:10.1123/ijsnem.21.4.311. https://pubmed.ncbi.nlm.nih.gov/21813914/

Nalbandian, M., & Takeda, M. (2016). Lactate as a Signaling Molecule That Regulates Exercise-Induced Adaptations. Biology (Basel), 5(4). doi:10.3390/biology5040038. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192418/

Northgraves, M. J., Peart, D. J., Jordan, C. A., & Vince, R. V. (2014). Effect of lactate supplementation and sodium bicarbonate on 40-km cycling time trial performance. J Strength Cond Res, 28(1), 273-280. doi:10.1519/JSC.0b013e3182986a4c. https://pubmed.ncbi.nlm.nih.gov/23660571/

Oliveira, L. F., de Salles Painelli, V., Nemezio, K., Gonçalves, L. S., Yamaguchi, G., Saunders, B., . . . Artioli, G. G. (2017). Chronic lactate supplementation does not improve blood buffering capacity and repeated high-intensity exercise. Scand J Med Sci Sports, 27(11), 1231-1239. doi:10.1111/sms.12792. https://pubmed.ncbi.nlm.nih.gov/27882611/

Painelli Vde, S., da Silva, R. P., de Oliveira, O. M., Jr., de Oliveira, L. F., Benatti, F. B., Rabelo, T., . . . Artioli, G. G. (2014). The effects of two different doses of calcium lactate on blood pH, bicarbonate, and repeated high-intensity exercise performance. Int J Sport Nutr Exerc Metab, 24(3), 286-295. doi:10.1123/ijsnem.2013-0191  https://pubmed.ncbi.nlm.nih.gov/24296517/