
educationMay 14, 202626:05pending
Jamie Lynn Sigler: How to Forgive Yourself and Rewrite Your Story
About this episode
Jamie Lynn Sigler is an award-winning actress best known for her role as Meadow Soprano on The Sopranos, as well as author and co-host of the MeSsy podcast with Christina Applegate.
Today, Jamie is encouraging you to stop hiding the heaviest parts of yourself. In a radically honest conversation with Tamsen Fadal, she speaks vulnerably about her experience privately navigating a multiple sclerosis (MS) diagnosis, the marriage that almost broke her, and how chronic illness has shaped her life, relationships, and mindset.
Jamie and Tamsen discuss:
- Why she kept her MS diagnosis secret for more than a decade
- Why James Gandolfini was the first person she trusted with her secret
- What Christina Applegate's own MS journey has meant to their friendship
- The realities of living with MS as a mother of two young, active boys
- The daily mindset practices that help her live well with a chronic illness
- The physical symptoms she manages day-to-day, including weakness, spasticity, and bladder issues
- What changes when you stop trying to be the good girl
- How to grieve the life you used to have while learning to love the one you have now
If you've ever carried something in silence because you were afraid of being judged or dismissed, you need to listen to this episode. You’ll walk away ready to take ownership of your narrative and ready to step into your next chapter with confidence, resilience, and clarity.
If you loved this episode, listen to: The Habits That Changed My Life After 50Stay connected with Tamsen:
Get Tamsen's newsletter filled with free tools to living better, feeling stronger, and knowing you’re never alone
Get Tamsen’s NYT instant bestselling book, How To Menopause
Free Resources from Tamsen
Watch all the episodes on YouTube
Follow Tamsen on Instagram
The Tamsen Show on Instagram
Follow Tamsen on TikTok
Get 15% off OneSkin with the code TAMSEN at https://www.oneskin.co/TAMSEN #oneskinpod
This show is sponsored by Midi Health. Visit https://joinmidi.com/TAMSEN today to book your personalized, insurance-covered virtual visit. Midi. The Care Women Deserve.
Stop putting off those doctor's appointments! Go to https://www.zocdoc.com/TAMSEN to find and instantly book a doctor you love today!
Medical Disclaimer:
The information provided in this podcast is for educational and informational purposes only and is not intended as medical advice. Always consult with a qualified healthcare professional regarding any medical concerns or treatment options. The views expressed by guests are their own and do not necessarily reflect those of The Tamsen Show.
Learn more about your ad choices. Visit podcastchoices.com/adchoices
Get every episode summarized
Each time The Tamsen Show publishes, we email you a written briefing from the transcript — the topics, who appeared, and any specific claims, with the ad reads skipped.
Email me new episodesFree for 3 shows. No card needed.
Hosts & guests
No transcript yet
This episode has not been transcribed. Request it and it moves to the front of the queue.
More episodes
More from The Tamsen Show

What Every Woman Should Know About Low Libido and the Pink Pill
The Tamsen Show
Sep 10, 202637:00completed

The Migraine Doctor: Botox, Supplements, Hormones & What Actually Works
The Tamsen Show
Sep 7, 202634:44completed

Brooke Burke on Living Her Dream, Getting Fired, and Rediscovering Herself
The Tamsen Show
Sep 3, 202639:00pending

5 Signs Your Career Is No Longer Right for You
The Tamsen Show
Aug 31, 202621:19pending