Loading...
Loading...

Kill your vices, sculpt your physique, and become unstoppable with my FREE 6-Step Daily Domination Blueprint.
Today I'm joined by metabolic scientist Dr. Latt Mansor to discuss all things ketones.
Latt holds a PhD in Physiology, Anatomy, and Genetics from University of Oxford and is the Research Lead at Ketone-IQ; a performance nutrition and metabolic health company.
His work has helped shed light on the role ketones play in cognitive function, physical performance, and metabolic health. And he's here to share how they impact recovery, mental clarity, and energy production.
We also dive into their role in heart health, metabolic disease, brain function, and more.
Find out why ketones are called "nature's superfuel", and how you can use them to supercharge your health, in today's episode...
Sponsors
AG1: Improve your gut health and immunity, and boost your energy and recovery at drinkag1.com/jay.
Marek Health: Take the path to better health, optimized performance, and increased longevity at marekhealth.com - code JAY at checkout for 10% off.
Want to work with me to transform your body and mind? Go here now.
You are listening to the Jay Faroujia Show, the podcast that helps high-achieving men
get lean-in jacked, build an unbreakable mindset, and become the man you're meant to be.
Black, give everybody a little quick go, kind of background, intro on yourself.
Yeah, sure. Lat Mansour, originally from Malaysia,
did my undergrad in Biotechnology from University of Nottingham in the UK,
did my Masters in Biotechnology also in Columbia University in New York,
and then I worked in Pharmaceutical Company called the Medicines Company.
I worked for them for about a year and a half before I decided to go back to school,
did my PhD or DFL in Physiology and Atomy and Genetics from University of Oxford in the UK.
Specifically looking at metabolism of type 2 diabetic heart in hypoxia, which is low oxygen
environments. And then after I graduated, I went back to Southeast Asia, Singapore and Malaysia
worked for three years in the startup environment, startup world, worked for a diabetes management
company for a year and a half, came out, started my own health tech for a year and a half,
and then I got introduced to Keton IQ or HVMN at that point. It was healthy, a modern nutrition,
the name of the company in 2019. They flew me out to San Francisco my first time there in June,
2019, interviewed me for the whole week, offered me the job at the end of the week, August 2019,
packed my stuff from Malaysia, took a one-way flight to San Francisco and rest his history.
Now here I am. I've been leading all the science efforts at Keton IQ since 2019,
overseeing all of our clinical collaborations, our scientific studies to make sure that all
those claims are substantiated, as well as all our scientific advisor, partnership and all of that.
How has your role changed and evolved since you started? What was it like at the beginning
compared to now? That's a great question. It has evolved so much. The titles remained the
title remained the same. It was research lead, but the role definitely changed quite a bit because
when I was hired, I was hired to be the principal investigator overseeing the six million dollar
contract with the department of defense. So they just scored this STTR phase two, which is a small
business contract with the military, with SOCOM Special Command looking at using Keton's to
improve physical and cognitive performance. So they needed a scientist to oversee the whole
operation. So they hired me for that role. So I oversaw that whole project for four and a half
years. It was supposed to be two and a half, but because of the pandemic, it got extended.
And since then, the role evolved from being a PI of a study to helping
run studies of our own. So right now, we have a appetite suppression study at University of
British Columbia. We have a heart failure study at University of Arhus in Denmark. And on top of that,
I think the biggest change that I've experienced within my job scope was content making and podcasting.
I was not expecting what we're doing now, like educating people at scale. I mean,
I've always wanted to do that. I think one of my biggest passion of wanting to be a scientist
was because I saw the void between science and application. There is a miscommunication or disconnection
between what people discover in the labs and what is actually being practiced, especially with
regards to chronic diseases and lifestyle interventions. So having the experience and opportunity
to be on podcasts and make contents and have people follow us and really engage with us with
questions that they are curious about metabolic health and how they could use the knowledge I know
to improve their lives. That has been quite life changing for me.
Do you remember the first time you made that transition? Like they said, you're going to start being
on podcasts. Yeah. So I think it was a shift from SEO. Because I remember when I joined,
they were all optimizing SEOs and Google search and blog posts and all of that. And then
TikTok came out, I think. And then it was like content, short form content. And then we found that
because of the nature of the product being a food product, but also very useful in the
biohacking space. A lot of our audience are big fans of podcasts. But also I think what changed
the landscape of podcasts was 2020 during the pandemic when everyone was listening to podcasts
like podcasts just blew up. And that was when we saw a lot of marketing dollars being used very
effectively, uh, was, you know, spending it on podcasts. And they were like, okay, well, you're
the subject matter expert. You are the metabolic scientist. Why don't you represent us at that
point that we're just standing me and the CEO. So the CEO would go on more business related
entrepreneurship podcasts and I'll go on more technical scientific podcasts. And then,
you know, over time, it became more and more natural. It became less and less, you know,
nerve wrecking. And here we are. Yeah. Where were you stressed out about it first?
I think I was definitely stressed out because I want to make sure that the information that I relay
was accurate, right? I want to make sure that, okay, let's say you asked me like, what study
showed what? I want to make sure that this is accurate. So in a way, I feel like I'm going into an
exam and oral exam where I have to memorize the facts. And then I realized all these people,
like, they give a lot of vague answers, a lot of ambiguous answers and a lot of like inaccurate
answers as well. And most of it is just clickbaits. So I was like, you know what? I can just relax
because I know more than that. Right. Right. Right. Yeah. All right. Well, let's get into some of the
latest research on key tones. Yeah. So we just finished a big study with KU Lewvin as a university
in Belgium. So that is in conjunction with our partnership with Visma Lisa bike team, which is a
two different team. So they're cyclists, professional cyclists. I believe they got a second last year
and then they won the year before. So we have been partnering with them and in conjunction with that,
we are researching how to use key tone IQ, the product to improve recovery and how does it affect
recovery with regards to endogenesis, which is new blood vessel formation. So we have found really,
really interesting results there. We saw an improvement in oxygen delivery because we had
these participants in a hypoxic room, also low oxygen room, have them exercise and then measure
the oxygen levels in their blood vessels. And we saw an improved delivery of oxygen into the
muscles, which is great for recovery, right? Because you want to make sure that your muscles and,
you know, or all the parts within your body that you're using energy to receive oxygen because oxygen
is needed for respiration in the mitochondria. So in order to create energy, you will need oxygen
as much as you will need the substrates itself, the fuel itself. So that's great. We are currently
in review waiting to be published. So once that's published, I'll be making more content around that.
As I said earlier, we've got appetite suppression study that's also wrapping up to show that
key tone IQ having a slight appetite suppression effect. Now, do not affect and do not expect the
same effect as an epic, right? But there is some form of appetite suppression where some people like
to use it for fasting, for example, intermittent fasting or for long fasting, like 24. I use it for
36 hours fast, which is great for me because it feels like cheating because I don't feel tired.
I don't feel hungry. I don't want an appetite suppression effect. I won't have
I haven't really noticed that when I've taken key tones, like I'm always hungry anyway. So
that's the funny part, right? For people who have shown, for the studies who have shown
appetite suppression effects, they were done on sedentary people. Whereas there was one study
that looked at overreaching, overtraining and training over time, over three weeks, they use
it post exercise and before bed. They actually saw the opposite. The people on key tones actually
had more calories going in. And as a result, they also had a compounding effect of increased
15% power output at the end of three weeks. So I feel like key tones is a very unique substrate where
it almost adapts to your situation, your circumstance. If you're sedentary, you are not using
a lot of energy. It helps you curb your appetite. Whereas if you are training hard and you are
eating right, it almost wants to help you build and recover. And it goes hand in hand with
that oxygen delivery as well. How many, I'm just thinking about training now. So how many times
a day can you use something like ether like one of those shots? There's always, you know,
you can always overdose on things, even water. So what we advise people is up to three shots per day.
I personally use more than that because a lot of the studies, they use body weight matched
dosing. So there's 0.3 grams per kilogram of body weight. So for me, I typically take between
three to five shots a day. I take one and a half or two shots, one with caffeine and one without
caffeine. So the one with caffeine has only five grams of ketones. And this one without caffeine has
10 grams. So I'll take one of each in the morning before my faster cardio that you make me do,
that that was a hard start. And then now I just can't stop because it just becomes a routine.
So I'll take one before my faster workout. I'll take one and you notice you feel better during
faster cardio when you take that? Yes, yes, absolutely. Especially if it's like 45, 15 minutes,
even zone two, when you're faster, you can feel that depletion of energy, right? You can feel the
hunger kicking in and the cortisol levels high. So when I take that, it smoothens out. And then go
straight into breakfast, which was great. And then I take one like before podcast or before work
or before meeting. So whatever. And then I'll sometimes I take one before workout, but usually that
during work kind of lasts me throughout the workout. And then I'll take two before bed.
Okay. Two before bed. A lot of people ask that. I'm always like cautious when I tell people
when I take two before bed, because they asked studies. Right now we are running a study with
Johns Hopkins sleep center looking at sleep apnea. So they found that ketogenic diet actually was
helpful in sleep apnea patients. So with obstructive sleep apnea, they're snoring, they're not
getting enough oxygen. And again, it comes back to the oxygen delivery. Yeah. So it's so interesting
because ketogenic also, there is a hypothetical effect of vasodilation. So it dilates your blood
vessels. It has been shown in animals. That's why I say hypothetically in humans, it hasn't been
specifically measured yet. In the recovery study from Belgium, we did measure it. They saw a
suppression of endothelian one, which is a compound that restricts your blood vessels.
So it allows your blood vessels to relax and dilate. And that increases blood flow. And
increases blood flow means increasing both the substrates and the oxygen delivery. So in
the sleep apnea patients, they saw that in ketogenic diet. So they want to replicate that
with ketone IQ and see what happens. And because it is not as stimulant, so a lot of people they
think, oh, it gives you energy. So you shouldn't take it before bed because it's not as stimulant
like caffeine. It doesn't affect sleep quality. Some people do anecdotally report more vivid dreams
after taking in ketones before bed. But I generally sleep better. And I found it helpful with
my recovery when I take it before bed. Wow. Okay. A couple of things here. We're talking about
blood flow. Does it improve sexual function in any way? We haven't measured that yet. Okay. But
technically, you're right. It could. Okay. Yeah. And then what about like pumps in the gym?
Pumps in the gym. I don't notice as much. But yeah, I don't notice as much in the pump in the
gym. Okay. But that's an interesting question. I also haven't really observed, observed,
you know, the pump. So it could be. Yeah. But then again, I don't know if it gets overshadowed,
if somebody takes pre-workout, right? If they take nitric oxide, like that's probably a much,
much stronger vessel dilator than ketones. Yeah. Yeah. And anything that can help with
sleep apnea is going to improve a lot of health outcome. Yeah. So many things get negatively impacted.
Exactly. Like obesity rates, heart disease, stroke, all of that like improved. Yeah. Wow.
Some people swear by taking a pre and post workout. They say it helps to recover taking a post
workout. In fact, the Visma Lisa bike to the France team, they specifically take it post workout
as recovery stress. Okay. More than a pre workout. Okay. Because I feel like people find that,
okay, pre workout, I get more focus. Great. But if I want to like maximize the effect
while not having to spend extra, then they sort of have a compounding effect of the recovery.
Because recovery effects compounds, right? Whereas acute, you do it then, then, then it's done
and over with, right? Yeah. So it's like a immediate energy when you do it for acute pre workout.
But then post workout, you are actually helping with the recovery and therefore having a compounding
effect over time. Yeah. So I was having a conversation with a colleague. This had to be probably
10 years ago now. And we were talking about the cognitive benefits of a ketogenic diet. But he,
like myself, had worked with so many athletes that we didn't find it practical to use a low carb
ketogenic diet. And you know, he brought up the point, which I agree with. He was like, wouldn't that
be like the highest level performance? If you could still be fueled by carbs and glycogen,
but also run on ketones at the same time. So I feel like you can kind of do that with like a more
carb-based diet than supplementing ketones without having, you know, just drink butter all day,
everything, right? Yeah. Yeah. Yeah. No, that's absolutely right. And some people swear by it,
I, the way, like my perspective on certain diets, not just keto diet,
even carnivore, or what, or plant, or paleo, or whatever, I think people should do it.
Only if they have a certain dysfunction that they're trying to fix, not to optimize per se,
because I think the human body is optimized to use both and like being very hybrid around it.
So a lot of people, they say, oh, I saw all my, this, this, this, this, this problems when I go
on keto. It's because you were over consuming carbs. And then now you take carbs out of the
equation, your body is then, you know, rebalancing itself, but then at some point, or their gut health's
just destroyed and they can't, they need to kind of do something extreme for a little while. Exactly.
I mean, exactly what you did with me, right? I was on, I grew up overweight, right? And so that's
something I didn't include in the intro. I grew up overweight. My mom's family were like, maybe
80% obese. A lot of them have diabetes. My late father died of stroke, and he had a heart attack
prior, a few years prior to that, prior to that. So I managed to lose weight quite late,
like about 22 years old. I started, you know, exercising and, and, and looking out for my diet,
but when I was looking out for my diet, I didn't know the right way. So all I knew was, oh,
I'm going to eat less carbs. And over time, I just eat less. So I just calorie restrict myself
over years and not eating carbs over the years. And when I started, first started training with Jay,
Jay was like, you need to add carbs in and my weight ballooned for the first two weeks. It went
up so fast because my body became very, um, car resistant. And it's not able to metabolize carb,
like a normal healthy person. But because of that, um, it also has that propensity to
really hold on to the fat because now my body's thinking that I'm always starving. So I can't
have a high metabolism or high basal metabolic rate and burn all these fat because I'm always
starving myself. So, um, even if I'm on the skinnier side of the scale, I am still having high
body fat percentage for the first time ever in my life of like 40 years of living. I managed to get
below 15% body fat because of Jay asking me to eat more carbs. So that's a lesson to be learned
there. Yeah. Absolutely. Yeah. It's just I find it in all the years I've been doing this. I find it
hard to optimize someone on super low carbs. If you're training hard, you know, perform it hard.
If people will get that high for 30 days, 60 days, 90 days, and then things kind of fall apart
then you're insulin resistant. You can't eat anything. Like you just said, you know, your metabolism
slows down, thyroid slows down. Um, so yeah, that's what I think is great about supplementing
with ketones and having carbs. So you just, you're just utilizing both fuel sources. It gives you
the option. Yeah. Right. It is always good to have options. And your body will always choose the
most efficient pathway granted if you're not dysfunctional, right? If you already screwed up,
you got to fix it first. And if you're perfectly healthy, it will always choose the most efficient
pathway. So even if you supply it with ketones or glucose, you don't even have to think and worry
about what your body is using. Your body will always use the most efficient fuel and then switch over
whenever it needs to. So having the option is always great. And I think a lot of people underestimate
the, uh, the power of having both, because metabolism is always not always a linear sort of pattern.
Right. You know, more is not better. Yeah. And always in a, in a way form, you need it to be in
an optimal zone. It's not always higher, the better. Same thing with, with, with, um, you know,
different exercises, right? You do low intensity. You burn more fat. You do high intensity. You burn
more glucose. So having those different options in your body allows you to, to really vary the way
you, you train and optimize different fields. Yep. Uh, because it's not a stimulant, it doesn't have
any negative effects like caffeine. Like if you're consuming too much caffeine, you're just skyrocketing
adrenaline cortisol. You're not going to get that. No. You are not going to get that, uh, you are not
going to get that crash. Um, when you have, you know, caffeine to half life gone, all the receptors
start opening up and then you start getting that fatigue again. Uh, you're not going to get the
jitters and all that because it is again, not a stimulant. Uh, but most importantly,
the stimulants simply stimulates you. It increases your heart rate, increases your cortisol, all
that increases your blood pressure, which is great for that quick burst of energy.
What it does not do is provide you with energy. In and of itself, it's not an energy source. It
cannot be metabolized and create ATP or energy in the cell. Keytones does. And that feeling of
energy that people feel subjectively, that it's not as some say not as powerful as a stimulant,
but it is literal energy being supplied into your body and to your brain. So that's the difference.
When it comes to my health, I want something I can trust. And that's why I choose AG1 with
science-backed ingredients and real benefits I can feel. AG1 makes it easy to support overall
wellness every day. And that's why I've been partnering with AG1 for so long. And AG1 is
offering new subscribers a free $76 gift when you sign up. You'll get a welcome kit,
a bottle of D3K2 and five free travel packs in your first box. So make sure to check out
drink AG1.com slash JAY to get this offer now. That's drink AG1.com slash JAY to take advantage of
this free offer now. Guys, if you are over the age of 40, you need to be getting your blood work done
at least twice a year if not every 90 days. You can't be guessing. You can't leave your health
to chance. And if you want to optimize everything, you've got to get your blood worked on so you
know what is actually going on under the hood instead of just guessing. Instead of just putting in
all the hard work in your training, in your diet, in your recovery, in your sleep, you could be
doing all those things but you just don't know about one, two, three, four major deficiencies that
you have or some kind of imbalance or something that is just off and that's what's holding you back.
So now you're just banging your head against the wall saying, why am I not feeling any better?
Why is my libido lagging? Why do I feel like shit? Why don't I have any energy? And the reality is
you can't know the answers to that question unless you get your blood worked on. So you got to get
dialed in, you got to get your blood worked on. That way you're not guessing and that's the only
way you're going to get fully optimized. What I recommend is you're going to go to marichealth.com
that is m-a-r-e-k-health.com. You're going to select the lab test, you're going to get whichever one
you think is best for you. Obviously, I recommend the most comprehensive one but whatever one makes
the most sense for you, get that done. At checkout, you're going to use the code J-A-Y to save.
That's marichealth.com. Use the code J-A-Y to save. Stop guessing, get your health dial then,
get your physique optimized, get your energy, your performance optimized and look and feel better
than ever. We've talked about, you mentioned endothelial cells and heart health. I want to get
into that a little more and I want to get into diabetes a little more. Anything else you can
share about heart health and like ketones, longevity, things like that. Yeah, very interesting.
If you Google a failing heart and ketones, you will find that in heart failure patients,
they up-regulate ketomatablism independent whether or not they're on ketodire. Even if they're
not on ketodire, they found that they up-regulate ketomatablism showing that the heart wants ketone
when it's failing. That gives us the idea that maybe ketone is a more efficient fuel source
in that particular situation and that is why we are running the study now with the University of
Harers in Denmark to look at 250 heart failure patients for 30 days on ketone IQ. It's a
eight multi-center trial for two years. It's a huge study and they got it funded. We didn't pay
for it. We just paid for the product. We want to be part of the study. They actually funded
via a Danish cardiovascular society and I think coming, cardiovascular disease is very close to
my heart given that my late father died from cardiovascular disease as well as my whole PhD
was surrounding cardiovascular disease. I think the effect of ketone one being a efficient fuel,
providing energy to the failing heart, it's one, and two, the effect of fossil dilation,
which again increases oxygen flow and blood flow into the heart. It's also another very important
point that may help with these heart failure patients. The crux of cardiovascular disease
is usually energy deficiency. It's because the blood flow is blocked. You have an artery blocked
so you have a heart attack and over time you have some form of occlusion. You have heart failure.
A lot of it is energy deficiency. We want to look at a more efficient fuel and we want to look
at better blood flow, both of which are being provided by ketones. This is very similar to
Alzheimer's disease where the brain is not getting enough oxygen. The brain is not getting enough glucose
or the brain is not metabolizing glucose efficiently or there is some form of insulin resistance
and then you provide ketones which uses a different transporter to enter the cell. Now you have
an auxiliary fuel that can compensate for that deficit. The way I see it is that how ketone
is helpful in these diseases or metabolic dysfunction is the way ketone could provide energy
in most cases where most people can't harness the energy from glucose because of the overconsumption
of glucose because of metabolic syndrome. That's super interesting. Just to put you on the
spot a little bit here, because you've studied so much about heart disease and things like that,
is there anything else? There are already instances of big guys over 40. Anything else that comes
on mine that's maybe a little bit outside of the box, if someone's like, my family has heart
disease, anything that comes on mine, I would suggest do this or don't do this. Other than the
kind of obvious stuff. Always get your health checked. The calcium score is very useful. Yeah,
it's a very useful parameter. I think they have a newer way to check the calcium to really have a
better accurate prediction of the blood vessels occlusions. That's first and foremost. Look out
for the risk factors, waste circumference, especially for guys that really increases the risks.
Obviously, smoking, drinking alcohol, those who would contribute to it.
And something that I learned from you, walking is underrated, especially for cardiovascular
health. Just having that one hour a day where your heart is pumping, not sprinting, but pumping
faster than a resting heart rate. I feel like that itself is like, I mean, your heart is full of
muscle. Every other muscle if you're training it. That is training your heart to be more efficient,
to be able to pump enough blood throughout your whole body. We always hear, it's almost a cliche
that stress kills. Do you do anything on a regular basis to kind of mitigate stress? Do you meditate?
Do you have any other context? I should meditate more than I do. I used to
a lot more. I do enjoy it. And every now and again, I do meditate. That definitely helps.
I think meditation itself does help, for sure. Breathful itself helped. But what really helped me
was through meditation, I'm able to change my perspective on how I see life. Does that make sense?
I'm being able to zoom out and look at my life almost in a third-person point of view,
where I almost detach myself from all the things that should be stressing me.
Looking at my job, looking at my bills, looking at the state of the world,
I'm like, these are just events. These are just part of life. These are just neutral
occurrences where you just need to be present and observe. And if you can change something,
change it to your desire and change it to optimize for yourself. But no and acknowledge
things that you can't change, you should just be there, observe and let it run its course.
Right. Rather than stressing about it, a lot of times we get so caught up in the media of it all,
and we get bombarded so much with it that we are all stressed out about it at World War 3 right now.
Can I change it? No, I can't even vote in this country. I'm not even, you know, your citizen,
right? So I can't change that. So what can I do? All I can do is be in my line and be present
like this week, I'm going to be in Expo West. People are going to ask about Kitson Science.
People are going to ask, how can they prevent metabolic diseases? I have that knowledge.
I can do what I can to help people. Yeah. Yeah. So so the meditation, the act of meditation does help
for sure. I think the change of perspective in life helped me way more. I love that answer man.
That's great. I love that. It looks diabetic diabetes a little bit more. Yeah. Yeah. I mean,
I grew up with family members like getting amputated when I didn't even know what diabetes was.
Wow. Yeah. I have family members who have to get amputated because of prolonged diabetes.
And a lot of times the sad thing is until now, some of them still believe that that is death
sentence. Right. And I told them I'm like, it is not like there are trials that have shown
people reverse their diabetes. They got off medication. Their blood glucose went back to normal.
Is it easy? No, nobody said it's going to be easy, but it's doable. So there is still a debate
on what chicken and egg which one comes first. Is it the increased calorie consumption that leads to
fat accumulation that leads to inflammation or the inflammation that leads to insulin resistance
that then leads to you not being able to metabolize all the carbs. So even if you're not eating a lot,
you're still keeping it as fat. So there is a debate as to which one comes first. And I think it
matters what demographic we're looking at as well. I think certain races, certain genetics
have a more propensity to develop one thing first before the other. So for example, I think there's
a study on like East Asians. East Asians, they have higher inclination to
multiply fat cells. White population on the other hand Caucasians, they have a higher
propensity to grow fat cells. So their cells are bigger. So you'll see a lot of like insulin
resistant. Usually you can see it physically. People who are obese, they have insulin resistance.
Whereas in Asia, you see them as skinny fat and they have insulin resistance because they have
more fat cells, but they're not big fat cells. So quantity and quality as well. I think that
genetic factor does play a role. And then obviously from insulin resistance over time,
your pancreas which increase insulin has to overcompensate to get more insulin because
your cells or your muscles, for example, your muscle uses up a lot of insulin, right? Your
uses up a lot of glucose. When you exercise, it registers the insulin to pull in enough glucose
to use it for energy. Now, what happens in insulin resistance individuals is that your muscles stop
listening to insulin. So even though you have a lot of insulin in, your muscles are not
taking all the glucose resulting in high blood glucose levels. Then when that happens,
you have high blood glucose and then you are exposing the rest of your body to high risk of infection
and nerve damage, kidney damage and all of that. So that's essentially the crux of diabetes,
where it's a vicious cycle of your muscles, your cells are not listening to insulin,
your pancreas secrete more so that it does have an effect. And then over time, you're still consuming
all that carbs, it feeds back. And then the pancreas at some point just fails. And in which case,
you just have a lot of these patients have to inject insulin themselves. So it's interesting.
It seemed like for a while there, diabetes was, oh, you just got to eat less carbs. And then
it seemed to be, well, no, it's all the processed food and the seed oils and carbs are fine.
And then all of a sudden, what people started talking about, well, in the 70s, now I'm drawing a
blanket, who it was, some doctor and some study, cured a million cases of diabetes with high
carbs, super low fat diets. So it's kind of all over the place. And then people point to like,
you just said they're like different populations. Well, they didn't have any incidents or
are very low incidents of diabetes until they started eating either carbs or more fat, right?
It's like all over the place. I think I think it's a combination of both. It's an over-consumption
of calories, and it can come from both carbs and fat. And I, somebody, I can't remember who,
but somebody posts a question where, you know, what in the world, or natural food, whole foods,
that comes high in carbs and fat. Naturally, you either get high protein and fat or just carbs.
So a lot of these processed food, you're right. They are engineered with carbs and fats,
and that they found to be addictive, and that's good for marketing and that's good for sales,
right? So the combination of that and then the density of the calories that comes with it
makes people want to eat more, and then internally creates a metabolic dysfunction that feeds more
onto that lifestyle. So I have a, I mean, trying to say that they're all right to a certain extent.
You're right. Exactly. Yeah. And a lot of people also don't realize that, yes,
what's going in matters and what your pancreas is secreting in terms of insulin
to counter that really matters, but also exercise. Like muscle is one of the biggest muscle,
one of the biggest organ that can mop up glucose and exercise has been shown again and again
to reverse insulin resistance. Right. Even even in people who are really late stage,
once they exercise, they saw that their muscles are starting to take back the glucose into the
muscles and start metabolizing it. Yeah. So it's as a matter of what's going in the input
and how you clear it within your body. You know what's interesting, obviously not a study of my
own experience in looking at people's blood work and then just talking to colleagues who have
seen blood work for years and years is so many times people on a lower carb higher fat diet come
back and their blood sugar numbers are just completely whacked and then you clean it up and get
them to lower their fat a bit and actually eat more carbs and it improves, which is counterintuitive
to like the mainstream narrative sometimes. It's really funny because you know I've been on
you know keto and low carb for a while and my cholesterol I'm granted I do have a family history
of high cholesterol and my cholesterol has always been tithering right above the upper boundaries.
So above 200. My latest blood test was my lipids was down, my cholesterol for the first time was
down to like 170. Nothing really changed apart from you know the macros that you gave me but that
even that like I've been on that for like two years and for it to like now only I'm seeing
improvement in my lipids which I found quite interesting. Nothing I noticed in my blood work was
my thyroid. So my TSH my thyroid stimulating hormone has halfed from 3.8 to 1.6 and my T3 and T4
maintained showing that I don't need as much TSH to stimulate my T3 and T4 and I found that
very fascinating. Do I know why exactly is it one of the supplements is it the lifestyle I think
is a combination of all that I can't pinpoint a single thing that can that changes it I wish
I can and I can make millions right right right but I think it's the combination of lifestyle change
diet the workout the active the active being active yeah and then all the whatever supplements I take
I do definitely think eating more carbs does help with that though for sure yeah the beauty of
being able to eat five six hundred grams of carbs I never would have thought that they would
would arrive yeah I'm trying to think if there's anything else I want to touch on in terms of
performance I mean you know you guys have stuff with with SWAT teams yes we are currently going through
a proposal by the Florida State University to run a study with the SWAT team down there
looking at cognition specifically cognition and also performance so we're going to test them
cognitively have their cognitive test have their accuracy all that make them exercise and then
look at their marksmanship look at their accuracy and then look at cognition when they're on
keys or IQ versus when they're on placebo so that is a super cool study proposal I can't wait to dig
into it will be filming content so that because FSU has one of the nicest biggest facility the
institute of sport sciences medicine as ISSM so I would love to go down because they can measure
all of like the DEX the VO2 max the hypoxic chain all of that stuff they they have it right so
looking forward to that one back to just you know for the average guy listening for workout
performance obviously you have more focus and energy but anything else you can talk about in terms
of like like benefits similar to Cree team where you're like oh I can get extra two reps or I'm not
as like I find I'm not as fatigued like 30 40 minutes into a workout something like that you know
like think things like that yeah hundred percent I think for endurance especially when people are
doing cardio or running cycling swimming or whatever they definitely have seen the more significant
effect where they can last longer yeah or they can go at the same pace but then they realize their
heart rates are lower which is super interesting so you know you know they're putting as much effort
technically yeah but their body is just more efficient wow and their heart health is much better
right so they're just more efficient at pumping blood throughout the body so that's for endurance
aerobic exercise we have one study published that showed improvement in power average power peak
power and reduce fatigue when they do the wing gate test that was with the University of North
Georgia and with that I'm going to say what I feel personally is when I take into an IQ before
my lips I feel like because of the focus and the cognitive clarity I can be more engaged and
present with my form so when I lift heavy especially yeah that makes a lot of difference that's
huge yeah yeah yeah I do I love that I didn't even think of that yeah yeah because because then I'm
like right because I usually lift around like five six seven pm quite late where I really had a
whole day of things yeah your mind will be thinking about whatever happened that day yeah consolidating
fixing problems whatever but with Kishan I'm like okay I'm locked in okay I'm doing I'm doing
a Romanian that lift yeah I need to be able to push my hips back need to go down need to stick to
the to the to the quads need to make sure my my back is not rounded all the stuff is multi-faceted
right so you need your brain to engage all these different parts and then do a proper app right so
I just remember this because I literally did this two days ago with a new program you gave me
I was like man you nailed it yeah literally I was watching the video because I was like looking at
the difference between remitted deadlift and stiff leg deadlift and the starting where they start
is different so so the form is one two is the fatigue index that we saw on the sprinting
and then I would say when I use it for so I usually lift for like about 15 minutes that's usually
with finish on my lips and I'll do a bit of cardio zone two during that time having the
ketone already in it makes it a breeze I don't I literally don't even think about don't even think
about like tiredness right whereas before and I think I told you sometimes when I text you sometimes
when I'm like yeah this like low carb day like especially when I just switch over during that cardio
is when I feel a bit like-headed I feel like okay my hands are getting clammy you know that's
the hypoglycemic like signs I'll go and get a protein ball right after but with ketones I usually
don't feel that wow that's huge yeah that's huge I was talking to a guy who's big in the keto space
maybe a month ago in New York actually and he mentioned something about using medical grade ketones
pro athletes and tendon repair is that something you guys have looked into you had to hurt about
no I have not he said it was kind of a new thing that they were looking into medical grade what makes
it medical yeah that's the thing because like this ones are you know obviously it's FDA grass
99.9% third party tested with the purity and all that for human consumption yeah so I wonder
what medical grade could be like what the next level could be and also I have so many questions
I'm like is it injecting into it or is it just I mean I don't know I thought what repair joint
repairs to say tendon repair yeah because tendon would be collagen would be like muscles and collagen
right and I don't I don't remember reading ketones being directly having or having
direct effect on these except for providing energy right but you still need the building blocks
and you need the trigger to start the repair yeah right which I don't think ketone can provide
but last year on another note another interesting fact was they they didn't animals using
beauty in dial actually the active ingredient in ketone IQ University of Toledo in Ohio they publish
two papers looking at animals given beauty in dial they saw epigenetic changes so it doesn't
only change physiologically but it affects on a DNA level they saw an improvement or increase
in fatty acid oxidation on an epigenetic level so they are the DNA is starting to translate
and create proteins that are related to fatty acid oxidation wow which in a long run I'm like
is that why I'm burning all this fat let's touch on TBI a little bit I mean this is interesting
to me because I have a lot of clients who are WWE and have had a lot of concussions before that
football players wrestlers all that yeah let's talk about that a little bit yeah we just finished
a pilot study with the Naval Health Research Center looking specifically at TBI so I'm still waiting
for the results on that but we also had ex-so-com members who has TBI long-term effects brain fog and
all of that and he swears by it he he would you know have a shot and the brain fog would go away
and he'll be able to focus so happy I'm happy to provide whoever whatever client you have just
try it I'll just give it to you Senator I think it's really it's a really powerful tool
as one ketones bypasses the blood brain barrier go straight to your brain that has been shown
because we had a TBI study in Australia actually two hospitals are running TBI studies and these
are patients who are just out they are in ICU they're not conscious and they had to like to feed
them and then they measure whether or not the ketones get into the cerebral spinal fluid
and they found yes so we know that the targeted organ is receiving ketones and then they're
going to measure like the improvement after we're using MRIs and all of that so we know that ketone
gets into your brain your brain loves ketones when it's present regardless of any other substrate so
it just takes up ketones regardless if you have glucose or fat or whatnot in your body and
function MRI also has shown that the different regions of your brain
get more active they talk to each other more so brain network stability increases when people
are on ketones well I would you suggest if someone like let's say someone text me later a
Monday night raw and they get a concussion not hopefully not have but would it be something
you're like start taking ketones yeah yeah take it within like for 34 hours like just take like
yeah two two shots yeah and like see how they feel like because what they have seen in concussion
especially acutely within like 24 hours 48 hours there is a huge spike in glucose metabolism in
brain the hypothesis is that the increasing glucose metabolism is one to create energy to mitigate
the damage and two is to shove glucose into the pentose phosphate pathway which is
used to to use for recovery so with the increasing glucose metabolism you can imagine if someone
is not as efficient in metabolizing glucose they're going to have a block there first and foremost
and then you're going to have a midterm damage now and then over time because there is spike like
I said in metabolism is always in a waveform right if there is a spike there's always going to be
a crash and that's what they observed about seven days later there will always be a high
poor metabolism of glucose and then there is an increase in lactate so they're using the brain is
using something else to create energy because they can't maintain that high level of glucose metabolism
for that long so imagine if now you provide ketones during that window where the brain needs energy
most now you have glucose and ketones even with insulin resistance ketones are not reliant
on insulin to get into the cell unlike glucose so you are now providing an alternative fuel
to make sure that your brain has enough energy to one mitigate the dimension to help with recovery
it's fascinating any other kind of common conditions that we haven't talked about the ketones
or benefit come on oh we've got sleep apnea we've got appetite we've got heart failure TBI
I think the big one nowadays is cognition I think everyone everyone realizes that
brain power is the way to go yeah you know it's I think people also you know
trying to catch up with AI where AI can do everything in seconds and you're like well you know
you got to you got to be useful and not not lose to AI or as we lose your job kind of thing right
so brain power a lot of people especially like the executives the CEOs the the silicon valleys
military they especially with military a lot of them they are physically fit already
yeah but what makes the difference is is how sharp you are during that high stress environment yeah
if they're in high altitude if they're you know haven't had food for a couple of days like
how functional is your brain to make split second decisions at that point yeah that's huge
now again my audience tends to be guys are age over 40 but also they don't have as things they
want to go all in so if some were to start ketones like what's the optimal like if you tell
if you tell me I'm gonna perform at the highest level I'll take 70 of those a day right like
so what what do you think they're good like first thing in the morning pre-training post-training
and bed something like that or yeah so I would start with I'll start with first thing in the morning
yeah and you can't have it with coffee a lot of people ask me this question they're like can I
have it with coffee yeah it works in just synergistically because like I said stimulant increases
your energy demand it doesn't provide the energy but ketones does so so you can take it you know
in the morning see how you feel productive productivity-wise and then you can sort of tell
how what the subjective difference is and then you can take it before workout because I feel like
workout it's probably you feel less in terms of the significant subjective feel just because
you're already like going all in you know you're like so many things happening your body is
already like exerting so much whereas if you're just taking it for productivity at the first
thing in the morning you're sitting down the only thing that's working is your brain so you can feel
it yeah right and then you combine it with your physical your your body and your brain kind of
work when you're working out then you'll get the benefit and then bed I was I would stay away
until your your body is get you it's used to ketone first okay yeah because like I said a lot
people they freak out because they're like oh my god my my dreams were so vivid yeah because the
brain was like active right so yeah so I would do one or two depending on how big you are like
I said a lot of these studies are body weight match a bigger guy they need more ketones okay so
I want to show you in the morning first thing and then I want to do before workout and then go
from there awesome warm his chain so how many pounds have you lost 30 pounds well I when I started
with you I was 185 okay I have the graph and all that to to to to I was 20 20 or yeah it was 20
24 no it was end of 2023 I think yeah and then I lost about 30 pounds of 185 now I'm hovering
around 160 I know we're trying to like get it down with higher carbs but because of my travels
and stuff it's yeah but I mean you're feeling great you look great I've the fitters I've been
in my life I think you know I wouldn't have thought that I would get absent at you know 41 right
you made it you know the stuff that you do the the work that you do the people that you've helped
um really helped me and I'm sure a lot of other people to visualize what is possible
at your age you know I always you know what people always talk about like manifestation and like
elder meditation while I can't explain it in with science I do believe that when you can visualize
something you are putting it in your realm of possibilities yes and when it is in your realm of
possibilities all you need to do is just work towards it yeah I think a lot of people they can't
imagine it so they can't achieve it but if you like I'm like yeah when I'm seeing like
socially I'm looking at you I'm looking at people like Eric Henman Michael Chernau you know all
this like super fed like in their 40s 50s I'm like I'm a human being that we're the same species
if they can do it I can do it yeah I just need to know how yeah now that I know that it's possible
yeah I just need to know the how to get from point A to B the problem is people normally don't see
the beat and they just keep going doing how then I'm like how do you know what the how that you know
is the right how yeah you know you don't even see that you're just walking left and right and you
never get that right you just get that you need to know where you're getting first such a great point
yeah I love it awesome man this was great thank you so much thanks thank you let everybody know
kind of where they can follow you where they can get the product all that yeah you can follow me
at latmanso l-a-t-t-m-a-n-s-o-r on all social media and you can get the product at keto.com
amazon if you want it online and if you want to retail you can get it from target uh sprouts uh
a lot of uh specialty bike shops and all that they have that as well so oh yeah thanks for listening
guys we'll talk to you next time guys I hope you enjoyed today's episode if you want to take
it a step further I invite you to apply for my elite coaching program where we work closely
together to completely transform your body mind and life go to j dot training right now for more
info that's j dot training and you can find all these links in the show notes thanks so much for
listening

The Jay Ferruggia Show

The Jay Ferruggia Show

The Jay Ferruggia Show