The Science Behind Inflammation and Aging With Deinde and Debut CEO, Joshua Britton

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Inflammation isn't just about redness and irritation—it’s a driving force behind premature aging. In this episode of Skin Anarchy, host Ekta sits down with Joshua Britton, CEO of Deinde, to explore how inflammation accelerates skin aging and how cutting-edge biotechnology is changing the skincare game.

Britton, a scientist-turned-beauty entrepreneur, founded Deinde under the biotech powerhouse Debut, with a mission to bring lab-driven skincare to consumers. With a team of 80 scientists and a platform screening 50 billion molecules, Deinde is developing targeted solutions for inflammatory aging, a process where chronic, low-grade inflammation breaks down collagen, deepens wrinkles and worsens conditions like rosacea, eczema, and acne.

One of their breakthrough discoveries? Naringenin—a potent anti-inflammatory compound that outperforms niacinamide in reducing inflammatory markers by 15 times. Clinically tested at a precise concentration, it significantly improves skin elasticity, reduces deep wrinkles, and restores baseline skin health—without the irritation caused by higher concentrations of traditional actives.

Britton also debunks skincare marketing myths, calling for science over hype. With trends like exosomes dominating the conversation, he emphasizes the importance of clinical validation over buzzwords, urging consumers to choose evidence-backed formulations over marketing gimmicks.

This episode is a must-listen for anyone looking to future-proof their skincare routine with biotech-driven solutions that work at the molecular level. Tune in to discover how Deinde is redefining the way we fight aging—starting with inflammation.

To learn more about Deinde, visit their website and social media. Don’t forget to subscribe to Skin Anarchy on Apple Podcasts, Spotify, or your preferred platform. Reach out to us through email with any questions.

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